Cord Blood News 11.47 December 5, 2019 | |
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TOP STORYInvestigators found that 455-nm blue light was effective for promoting proliferation, migration, and tube formation of human umbilical vein endothelial cells co-cultured with MSCs. [Stem Cell Res Ther] Full Article | |
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PUBLICATIONS(Ranked by impact factor of the journal)Scientists compared the baseline osteogenic potential of MSC from Wharton’s jelly (WJ) and bone marrow cell sources by cytological staining, quantitative real-time PCR and proteomic analysis, and assessed chemical and biological strategies for priming undifferentiated WJ-MSC. [Stem Cell Res Ther] Full Article Engrafted umbilical cord Wharton’s jelly MSCs (uMSCs) also illustrated comparable effect to restore the flow perfusion and augmented vascular endothelial growth factors-A, -B, and -C expression. Notably, the combination of miR29a and the uMSCs treatments revealed the utmost renovation of limbic flow perfusion. [Int J Mol Sci] Full Article A comparative study on the metabolomic and bioactive molecules/factors content of the secretome of MSCs derived from two expanding sources: the umbilical cord stroma and the dental pulp is presented and discussed. [PLoS One] Full Article The aim of this study was to select the reference gene for Wharton’s Jelly-derived MSC that were undergoing transduction and differentiation. In this work, the expression of 32 genes was analyzed, of which two, which had the most stable expression level, were selected. [Mol Biol Rep] Abstract The authors investigated the differences of biological characteristics in human umbilical cord MSCs (UCMSCs) and stem cells from human exfoliated deciduous teeth (SHEDs). UCMSCs and SHEDs were identified by flow cytometry. [Biochem Cell Biol] Abstract Subscribe to one of our other 19 science newsletters such as Hematopoiesis News & Cell Therapy News. | |
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REVIEWSReview of the Small-Molecule Nicotinamide for Ex Vivo Expansion of Umbilical Cord Blood The authors review the data for existing and developing ex vivo expansion techniques, with a focus on the pre-clinical and clinical data for nicotinamide-mediated cord blood expansion across both malignant and benign hematologic indications. [Exp Hematol] Abstract Visit our reviews page to see a complete list of reviews in the cord blood research field. | |
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INDUSTRY NEWSAkari Therapeutics, Plc announced the design of a pivotal Phase III pediatric trial in HSCT-TMA following a FDA End-of-Phase II meeting. [Akari Therapeutics, Plc] Press Release Boston Biomedical, Inc. announced that the company has entered into an alliance in oncology research with three world-leading oncology centers of excellence – Columbia University, Harvard University and The Wistar Institute. [Boston Biomedical, Inc.] Press Release | |
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POLICY NEWSChinese Universities with Military Ties Classed as ‘Risky’ Collaborators Forty-three Chinese universities should be considered ‘very high’ or ‘high’ risk collaborators because of their involvement in research for military and defence purposes, according to an Australian think tank. [Nature News] Editorial Elsevier Progresses in Open-Access Deal Making The scholarly publisher has announced several new licensing agreements in both Europe and the US, but some major academic groups are still without contracts and access to journals. [The Scientist] Editorial
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EVENTSNEW Understanding Endothelial Cell Diversity: Regulation and Regenerative Potential Visit our events page to see a complete list of events in the community.
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JOB OPPORTUNITIESNEW Professor – Regenerative Medicine (University of Southern Denmark) Scientist – Hematopoietic Stem and Progenitor Cell Biology (STEMCELL Technologies Inc.) Head of Laboratory – Cell Therapies (NHS Blood and Transplant) Research Fellow – Iron-Altered Hematopoiesis (New York Blood Center) Doctoral Student Position – Immunology and Gene Therapy (Karolinska Institutet) Postdoctoral Fellow – Erythropoiesis (Mount Sinai School of Medicine) PhD Studentships – Molecular and Cell Biology (University of Oxford) Faculty Position – Stem Cell Biology and Regenerative Medicine (Yale University School of Medicine) Research Assistant – Stem Cells and Engineering (New York Blood Center) Recruit Top Talent: Reach potential candidates by posting your organization’s career opportunities on the Connexon Creative Job Board at no cost.
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