| Vol. 11.26 – 17 July, 2020 |
| |
|
|
| Scientists found that elevated Skp2 abundance in prostate cancer cells destabilizes IDH1 to favor glycolysis and subsequent tumorigenesis. [Cell Research] |
|
|
|
| PUBLICATIONSRanked by the impact factor of the journal |
|
|
|
| The authors showed that the variant rs72725854 was present in a prostate cancer-specific enhancer at 8q24 locus. [Nature Communications] |
|
|
|
| Knockdown of MYC expression in prostate cancer cells increased the expression of MEIS1 and increased the occupancy of MYC at the MEIS1 locus. [Oncogene] |
|
|
|
| Scientists revealed that overexpression of WAP four-disulfide core domain 2 (WFDC2), and addition of recombinant protein HE4 could significantly inhibit prostate cancer metastasis in vivo and in vitro. [Cell Death & Disease] |
|
|
|
| Investigators demonstrated that nucleolin (NCL) was expressed on the surface of all three tested cell lines and that NCL inhibition resulted in reduced proliferation and migration. [Cancers] |
|
|
|
| Benign neuroendocrine cells expressed significantly lower quantified androgen receptor levels compared with paired benign luminal cells. [Prostate] |
|
|
|
| Coculture of the primary stromal cells with benign human prostate epithelial cell lines BHPrE1 or benign prostatic hyperplasia (BPH)-1 was performed in three‐dimensional Matrigel to determine the impact of primary stromal cells derived from BPH on epithelial proliferation. [Prostate] |
|
|
|
| Overexpression of CXCL12γ promoted the reprogramming of cells with a differentiated luminal phenotype to a nonluminal phenotype in both prostate and mammary epithelial cells. [Prostate] |
|
|
|
| Scientists investigated the combined effect of curcumin and metformin on the LNCaP prostate cancer cell line. LNCaP cells were treated with curcumin, metformin, and their combination at different concentrations. [Nutrition and Cancer-An International Journal] |
|
|
|
|
| The molecular underpinnings of how the liver aids and protects prostate cancer cells seeding, colonization and resistance was discussed. [Seminars in Cancer Biology] |
|
|
|
| The authors summarize the current knowledge of therapeutic induction and intracellular pathways of androgen receptor-mediated cellular senescence. [Cancers] |
|
|
|
|
| Funding agencies behind the radical open-access initiative Plan S have announced a policy that could make it possible for researchers to bypass journals’ restrictions on open publishing. [Nature News] |
|
|
|
| Some researchers worry students will miss out on certain practical and problem-solving skills and won’t be able to judge whether the hands-on work of a scientist is a good fit for them. But instructors are developing high-tech ways to simulate the field and lab experiences. [Science Insider] |
|
|
|
|
| October 20 – October 21 Virtual |
|
|
|
|
|
| European Molecular Biology Laboratory – Hinxton, Cambridge, United Kingdom |
|
|
|
| Rutgers Cancer Institute of New Jersey – Rutgers, New Jersey, United States |
|
|
|
| University of Maryland, Baltimore – Baltimore, Maryland, United States |
|
|
|
| Berlin School of Integrative Oncology Charité – Berlin, Germany |
|
|
|
| West Virginia University – Morgantown, West Virginia, United States |
|
|
|
|