| Vol. 13.13 – 06 April, 2021 |
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| The authors report that C3G downregulation promoted the acquisition of a more mesenchymal phenotype that enhanced the migratory and invasive capacity of glioblastoma cells. [Cell Death & Disease] |
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PUBLICATIONSRanked by the impact factor of the journal |
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| Investigators found that MSCs did not influence the proliferation of mucosal-associated invariant (TMAIT) cells but strikingly induced an activated phenotype with an increased expression of CD69, TNF-α, IFN-γ, and granzyme B. [Stem Cell Reports] |
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| The heterogeneity and the characteristics of cultured umbilical cord MSCs and the cognate human umbilical cord tissue at single‐cell resolution remains poorly defined. [FEBS Journal] |
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| Scientists found that IL-1β enhanced adhesion of human MSCs via increased focal adhesion contacts in an α5β1 integrin-specific manner. [Scientific Reports] |
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| Researchers found that IL-1β enhanced adhesion of human MSCs via increased focal adhesion contacts in an α5β1 integrin-specific manner. [Scientific Reports] |
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| Human umbilical cord (HUC)-MSCs were separated from the umbilical cord using the adherence method. Surface markers of HUC-MSCs were detected by flow cytometry for MSC identification. [Cancer Biotherapy and Radiopharmaceuticals] |
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| The authors showed that stents releasing exosomes derived from mesenchymal stem cells in the presence of reactive oxygen species enhanced vascular healing in rats with renal ischemia-reperfusion injury, promoting endothelial cell tube formation and proliferation, and impairing the migration of smooth muscle cells. [Nature Biomedical Engineering] |
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| Researchers comparatively assessed how the inflammatory environment present in acute respiratory distress syndrome (ARDS) lungs versus the lung environment present in healthy volunteers alters MSC behaviors. [European Respiratory Journal] |
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| Five groups of pigs were studied after 16 weeks of renovascular disease (RVD), RVD treated four weeks earlier with either percutaneous transluminal renal angioplasty or MSC-derived extracellular vesicles, and normal controls. [Cells] |
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| Mouse clonal MSCs were cultured on a Cytodex 3 microcarrier in a spinner flask for a suspension culture under hypoxia condition to increase mass productivity. [Bioprocess and Biosystems Engineering] |
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| The authors provide a detailed overview of the recent advances in microengineering of autologous stem cell-based tissue engineering platforms for the repair of damaged cardiac tissue. [Biomedicine & Pharmacotherapy] |
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| Athersys, Inc. announced that its partner HEALIOS K.K. has completed enrollment in the ONE-BRIDGE study in Japan evaluating MultiStem® in patients with acute respiratory distress syndrome (ARDS) caused by pneumonia. [Athersys, Inc] |
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| September 5 – 8, 2021 Exeter, England, United Kingdom |
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| Rutgers University – New Brunswick, New Jersey, United States |
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| STEMCELL Technologies, Inc. – Vancouver, British Columbia, Canada |
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| University of Chicago – Chicago, Illinois, United States |
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| Nanyang Technological University – Singapore, Singapore |
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| NIH National Institute of Allergy and Infectious Diseases – Bethesda, Maryland, United States |
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