| MiR-126 expression, as well as EGFL7, in systemic sclerosis scleroderma-MVECs and skin, was significantly down-regulated in association with increased expression of sprouty-related protein-1 and phosphoinositide-3 kinase regulatory subunit 2 and diminished response to VEGF. [Journal of Cellular and Molecular Medicine] |
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| The authors investigated the role of high shear stress (HSS) in atherosclerotic plaque formation. In vitro modeling used HUVECs and vascular smooth muscle cells exposed to HSS using a parallel‑plate flow system. [Molecular Medicine Reports] |
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| Researchers used a modified approach to differentiate induced pluripotent stem cells into corneal endothelial-like cells (CECs). After the identification of differentiated CECs, the CECs were injected into the anterior chambers of the eyes of a rabbit model of bullous keratopathy. [Stem Cells and Development] |
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| Scientists discuss the evidence for nitric oxide as a critical player of placental development and function, with a special focus on endothelial nitric oxide synthase vascular effects. [Journal of Cellular Physiology] |
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| The emerging role of bone morphogenetic proteins (BMP) signaling in lymphatic vessel biology will be highlighted within the framework of BMP signaling in the circulatory vasculature. [International Journal of Molecular Sciences] |
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| The authors review endothelial cell responses to substrate-derived biophysical cues, namely topography, curvature, and stiffness, as well as to flow-derived stresses, notably shear stress, pressure, and tensile stresses. [Communications Biology] |
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| The annual Vagelos Precision Medicine Pilot Grants have been awarded to five teams of VP&S researchers conducting innovative basic science, translational, and clinical research across multiple diseases, from novel cancer therapeutics to health disparities research. [Columbia University Irving Medical Center] |
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| July 12 – 15, 2021 Virtual |
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| Oklahoma Medical Research Foundation – Oklahoma City, Oklahoma, United States |
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| University of Pisa – Pisa, Italy |
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| Brigham and Women’s Hospital – Boston, Massachusetts, United States |
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| Gilead Sciences, Inc. – Foster City, California, United States |
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| University of Nebraska Medical Center – Omaha, Nebraska. United States |
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