| Vol. 7.34 – 27 September, 2021 |
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| By forced expression of the ectodysplasin-A in human epidermal keratinocytes sweat gland (SwG) culture medium, human epidermal keratinocytes were efficiently converted into SwG cells. [Advanced Science] |
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PUBLICATIONSRanked by the impact factor of the journal |
| DERMAL STEM CELLS & TISSUE REGENERATION |
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| Norrie disease causes deafness, blindness, and intellectual disability. Scienitsts showed that Norrie disease protein controls a network of transcriptional regulators required for maturation and maintenance of cochlear hair cells. [Proceedings of the National Academy of Sciences of the United States of America] |
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| Researchers conducted culture experiments that proved epidermal growth factor receptor (EGFR) activation drove human keratinocyte stem cell motility. [Journal of Cell Biology] |
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| The authors used a highly specific integrin α5β1 peptidomimetic combined with nanopatterned hydrogels to show that keratinocyte sheets regulated their migration ability at an optimal integrin α5β1 nanospacing. [eLife] |
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| Scientists examined the ability of three different G-protein-coupled receptor (GPCR) agonists to reverse signaling inhibition and ameliorate rash induced by epidermal growth factor receptor inhibitors (EGFRi). [Acta Pharmacologica Sinica] |
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| Researchers investigated whether mechanical energy transported by low intensity ultrasound could generate a mechanical stress able to induce the release of inflammatory cytokine such as interleukin-6 in the human keratinocyte cell line, HaCaT. [Scientific Reports] |
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| The authors used striped catfish to establish an ex vivo skin explant tissue culture model to explore host pathogen interaction. They concluded that this ex vivo skin explant model could serve as a teleost skin infection model for monitoring pathogenesis under various infection conditions. [Scientific Reports] |
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| Investigators constructed a cell model of hypertrophic scar (HTs) and explored the role of Nesprin-2 in this process. Myofibroblasts and fibroblasts were isolated from HTs and healthy skin tissues of the same patient. [International Wound Journal] |
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| The insect-derived peptide poecilocorisin-1 (PCC-1) did not induce toxicity in the human epithelial cell line HaCaT, but its potential as an anticancer agent was confirmed through specific effects of antiproliferation, apoptosis, and cell cycle arrest in two melanoma cell lines, SK-MEL-28 and G361. [Scientific Reports] |
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| The effects of Larrea divaricata, polyphenols and quercetin-3-methyl ether were assessed on B16F10 melanoma cells by determining the proliferation, viability, apoptosis induction and the expression and phosphorylation of STAT3. [Natural Product Research] |
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| Scientists highlight how morphogenetic processes are achieved by cell-shape changes, cell rearrangements, and oriented cell division. They describe approaches that have the potential to engineer 3D tissues for both basic science and translational purposes. [Current Biology] |
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| Sebia, a world leader in diagnostics in the fields of multiple myeloma and chronic diseases, and Metafora biosystems announced a strategic partnership to develop a portfolio of in vitro diagnostics solutions based on Metafora’s technology platform. [Sebia (BioSpace, Inc.)] |
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| Anthenex launched Klisyri® in Germany and the UK. Klisyri received approval by the European Commission and the UK Medicines & Healthcare products Regulatory Agency in July and August of 2021, respectively, for the topical treatment of actinic keratosis of the face and scalp in adults. [Athenex, Inc.] |
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| October 5 – 6, 2021 Virtual |
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| The University of New Mexico – Albuquerque, New Mexico, United States |
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| Novo Nordisk – Indianapolis, Indiana, United States |
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| University of Minnesota – Austin, Minnesota, United States |
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| University of Pennsylvania – Philadelphia, Pennsylvania, United States |
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| University of Colorado – Aurora, Colorado, United States |
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