| Vol. 13.45 – 16 December, 2021 |
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| Human cord blood CD34+ cells were co-cultured with mesenchymal stromal cells (MSC) wild type or hypoxia-inducible factor-1α-MSC (4:1) for 72 hours. Viability, cell cycle, ROS expression and immunophenotyping of key molecules involved in engraftment were evaluated by flow cytometry in CD34+ cells. [Stem Cell Research & Therapy] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| Investigators manufactured neprilysin gene-enhanced human umbilical cord-derived MSCs and intravenously transplanted them in Aβ1-42-injected Alzheimer’s disease animal models. [Stem Cells International] |
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| Villous cytotrophoblast (vCTB) cells fuse to generate and maintain the syncytiotrophoblast layer required for placental development and function. Scientists demonstrated that KLF6 was necessary for cell fusion in human primary vCTB and in the BeWo cell line. [Placenta] |
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| Scientists revealed that the levels of 5-methylcytosine (5mC), were significantly increased coupled with decreased activity of Ten-Eleven Translocation (TETs) enzymes that principally functioned by oxidizing 5mC in the obese placenta, consistent with hypoxia-induced genome-wide DNA hypermethylation observed in varied types of cells and tissues. [Reproductive Toxicology] |
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| Researchers evaluated the replication kinetics of Zika virus and the related encephalitic flavivirus West Nile strain Kunjin virus in early-term placental cell lines. [Virology Journal] |
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| The study included 21,012 newborn screened babies for congenital hypothyroidism starting from September 2013 until March 2019. Both cord-blood and heel-prick TSH were collected from each newborn. [Journal of Clinical Laboratory Analysis] |
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| In the last two decades, fetal amniotic fluid stem cells progressively attracted attention in the context of both basic research and the development of innovative therapeutic concepts. [Current Stem Cell Research & Therapy] |
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| FibroBiologics, introduced its scientific advisory board (SAB). Comprised of world-renowned scientists and clinicians, the SAB will provide the company with guidance on current and planned development programs focused exclusively on fibroblast-based cell therapies. [FibroBiologics, Inc.] |
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| Essent Biologics™, announced it has entered into a global distribution partnership agreement with the Amnion Foundation, a non-profit cell bank specializing in birth-tissue related cells and services. [Essent Biologics] |
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| March 9 – 11, 2022 Melbourne, Victoria, Australia |
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| MRC London Institute of Medical Sciences – London, England, United Kingdom |
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| Dana-Farber Cancer Institute – Boston, Massachusetts, United States |
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| University of Calgary – Calgary, Alberta, Canada |
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| Dana-Farber Cancer Institute – Boston, Massachusetts, United States |
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| Icahn School of Medicine at Mount Sinai – New York, New York, United States |
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