| Vol. 14.04 – 17 February, 2022 |
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| Investigators used whole genome bisulfite sequencing in placenta samples from prospective autism spectrum disorder (ASD) studies to discover a previously uncharacterized ASD risk gene, LOC105373085, renamed NHIP. [Genome Biology] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| The authors investigated the association of placental pathological findings with infantile neurodevelopment during the early 40 months of life. For obtaining placental blocks, scientists carried out random sampling and assessed eleven pathological findings using mixed modeling. [Scientific Reports] |
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| Researchers determined whether expression of epithelial-mesenchymal transition-associated genes in the extravillous trophoblast cells of early onset preeclamptics shows a less mesenchymal, more epithelial phenotype compared to control pregnancies. [Placenta] |
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| Scientists investigated the reaction of cord blood mononuclear cells (MNC) to stimulation with group B streptococcus (GBS) in comparison to that of MNC from adult blood with focus on the proliferative response in an in vitro infection model with heat-inactivated GBS. [Pediatric Research] |
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| The authors investigated the effects of human adipose tissue and umbilical cord-mesenchymal stem cells on neuropathic pain and its mechanisms using rat models of partial sciatic nerve ligation. [PLoS One] |
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| Human umbilical cord mesenchymal stem cells treatment significantly alleviated inflammation, reduced serum thyroid antibody levels, and decreased the ratios of IL-17α+/CD25+FOXP3+ cells and serum IFN-γ/IL-4 in experimental autoimmune thyroiditis rats. [Endocrine Journal] |
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| Investigators summarize specific functions and research directions regarding umbilical cord blood-derived exosomes, and their potential associations with pregnancy complications. [Reproductive Sciences] |
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| IMAC Holdings, Inc. announced that it has completed the second cohort of its Phase I clinical trial for its investigational compound utilizing umbilical cord-derived allogenic mesenchymal stem cells for the treatment of bradykinesia due to Parkinson’s disease. [IMAC Holdings, Inc.] |
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| March 13 – 18, 2022 Ventura, California, United States |
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| Singapore-MIT Alliance for Research and Technology (SMART) Centre – Singapore, Singapore |
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| George Mason University – Prince William, Virginia, United States |
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| Stanford University – Stanford, California, United States |
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| Penn State College of Medicine – Hershey, Pennsylvania, United States |
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| Albert Einstein College of Medicine – Bronx, New York, United States |
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