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Vol. 14.04 – 2 February, 2023
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Liquid chromatography-mass spectrometer was applied to determine the differentially expressed proteins between hepatocellular carcinoma tissues and corresponding adjacent tissue. [Molecular Cancer]
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PUBLICATIONSRanked by the impact factor of the journal
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Scientists proposed a novel ECM-inspired injectable hydrogel for adipose-derived stem cells (ADSCs) encapsulation and rheumatoid arthritis treatment.
[Advanced Science]
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Investigators demonstrated construction of a benchtop LEGO 3D bioprinter for additive layer manufacture of a 3D structure containing viable human skin cells within a hydrogel scaffold.
[Advanced Materials Technologies]
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The macrophage-derived glycoprotein nonmetastatic melanoma protein B captured by fibrotic ECM might activate resident normal fibroblasts around the fibrotic foci.
[Communications Biology]
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IL-1β was utilized to induce chondrocyte inflammation. The cytotoxicity of indole-3-propionic acid on rat chondrocytes was assessed. RT-qPCR, Griess reaction, ELISA, Western blot, and immunofluorescence were performed to evaluate the expression of inflammatory factors and stromal proteins.
[Molecular Medicine]
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Ex vivo cultured, mesenchymal stem cell-loaded 3D bioprinted structures remained intact, supported cell survival and contained de novo synthesized extracellular matrix components and migrating cells throughout the observation period.
[Macromolecular Bioscience]
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Using a quantitative proteomics approach, researchers identified cathepsins as key determinants of phagosome maturation in primary peritoneum-, lung-, and brain-resident macrophages.
[Life Science Alliance]
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Investigators established bovine lung tissue decellularization for the first time via pursuing four different protocols and characterization of reconstituted decellularized lung ECM hydrogels for biochemical and mechanical properties.
[ACS Applied Bio Materials]
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The authors investigated the functional role of Igf1 in fibrocartilage stem cells for temporomandibular jointcartilage growth and homeostasis by lineage tracing using Gli1-CreER+; Tmflfl mice and conditional Igf1 deletion using Gli1-/Col2-CreER+; Igf1fl/fl mice.
[Journal Of Bone And Mineral Metabolism]
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Spermatogonial stem cells were cultured on the human decellularized testicular matrix for four weeks. The viability and the expression of differentiation genes were evaluated by MTT and real-time PCR, respectively. [Artificial Organs]
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Emerging evidence suggests that alterations in metabolism are not only a feature of but also play an influential role in the pathogenesis of renal fibrosis. [FEBS Open Bio]
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Dr. Yongho Bae, assistant professor of pathology and anatomical sciences, has been awarded a five-year, $2.9 million grant from the National Heart, Lung and Blood Institute to continue his research into the effects of arterial stiffness on cardiovascular disease.
[University of Buffalo]
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June 4 – 7, 2023 Heidelberg, Germany
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Fred Hutchinson Cancer Center – Seattle, Washington, United States
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Beckman Research Institute – Monrovia, California, United States
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Essen University Hospital – Essen, Germany
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Ottawa Hospital Research Institute – Ottawa, Ontario, Canada
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European Molecular Biology Laboratory – Barcelona, Spain
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