HomeNewslettersImmune Regulation News<em>In Vitro</em> Modeling of CD8<sup>+</sup> T Cell Exhaustion Enables CRISPR Screening to Reveal a Role for BHLHE40
The authors established an in vitro model of chronic stimulation and benchmarked key phenotypic, functional, transcriptional, and epigenetic features against bona fide in vivo exhausted CD8 T cells.