Laurisa Dohm

[Scientific Reports] Researchers investigated the effects of green cocoon-derived sericin on human keratinocytes using lactate dehydrogenase activity to indicate damage reduction.

[Archives Of Biochemistry And Biophysics] Cells grown on plates coated by molecular collagen I, but not fibrillar collagen I, acquired certain resistance against UVB damages, as shown by increased survival and reduced apoptosis.

[Nature Communications] Investigators identified ANKRD1 as a mesenchymal-specific transcriptional coregulator under direct androgen receptor negative control in human dermal fibroblasts and a key driver of cancer-associated fibroblasts conversion, independent of cellular senescence.

[Cell Death & Disease] In an imiquimod-induced psoriasis mouse model, saracatinib effectively blocked mixed lineage kinase domain-like protein (MLKL) phosphorylation and inflammatory responses in vivo.

[JCI Insight] Scientists identified ITGA3 gene as marked by a super-enhancer element in the Epgn3 invasive cells. Silencing of ITGA3 enhanced invasiveness in both in vitro and in vivo systems suggesting it as a negative regulator of invasion.

[Current Opinion In Cell Biology] Scientists focus on the key cytoplasmic and nuclear mechanosensitive structures that are critical for the mammalian skin development and homeostatic maintenance.