| Vol. 15.44 – 14 November, 2023 |
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| Scientists postulated that melatonin has the potential to enhance the repair of osteoporotic bone defects by restoring the mitochondrial function of bone marrow-derived MSCs. [Journal Of Pineal Research] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| Researchers compared the efficacy of human adipose MSCs and human umbilical cord MSCs in vitro and in corneal transplantation models to explore the underlying molecular mechanisms and provide a powerful strategy for future clinical applications. [Stem Cell Research & Therapy] |
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| The regenerative properties of chitosan-alginate composite hydrogels in skin wound healing under normoxic and hypoxic conditions were investigated in vitro. [Stem Cell Research & Therapy] |
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| In vitro investigations disclosed that Kaempferol effectively enhanced mineralization and alkaline phosphatase activity in bone-marrow MSCs exposed to titanium particles. [European Journal Of Medical Research] |
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| Investigators determined the concentration that inhibited 17% of cell viability and investigated the effects of arsenic acute exposure on adipose-derived human MSCs differentiated in vitro into mature adipocytes and treated with sodium arsenite. [Toxicology] |
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| Scientists demonstrated that MAP microgel diameter could be tuned to control scaffold pore size and, in turn, modulate MSC survivability, proliferation, metabolism, and migration, thereby enhancing bioactivity and guiding future applications of MAP for regenerative medicine. [Advanced Biology] |
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| | Investigators identified the potential molecular basis of how human umbilical cord MSC-exosomes improved antiphospholipid antibody-induced placental injury and highlighted the functional importance of the miR-146a-5p/TRAF6 axis in the progression of obstetric antiphospholipid syndrome. [Journal Of Nanobiotechnology] |
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| Researchers assessed the effect of human MSCs and MSC-extracellular vesicles on CD4+ T cells from patients with rheumatoid arthritis. [Stem Cells Translational Medicine] |
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| Mildly hypomethylated bone marrow-derived MSCs and their secretome were independently transplanted or infused in premature ovarian failure mice, established via cisplatin-mediated gonadotoxicity. [Reproductive Sciences] |
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| The authors describe the similarities and differences between various dental-derived MSCs (DSCs). Their focus was on the secretome of DSCs and their applications in cell therapy for neurological disorders. For neuro-regenerative purposes, the secretome of different DSCs has been tested. [Stem Cell Reviews And Reports] |
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| The designation covers using MSC-derived small extracellular vesicles loaded with short and modified interfering RNA targeting the phosphatase and tensin homolog (PTEN) protein for acute spinal cord injury, as implemented in the company’s ExoPTEN drug under development. [NurExone Biologic, Inc. (Globe Newswire)] |
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| December 4 – 6, 2023 Vienna, Austria |
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| University of California – Los Angeles, California, United States |
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| China Pharmaceutical University – Nanjing, Jiangsu, China |
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| National University of Singapore – Singapore, Singapore |
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| University of Turku – Turku, Finland |
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| Stanford Medicine – Stanford, California, United States |
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