| Vol. 14.18 – 21 November, 2023 |
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| Researchers proposed a tissue engineering strategy using uterine endometrium-derived mesenchymal stem/stromal cells delivered with degradable poly L-lactic acid-co-poly ε-caprolactone and evaluated the immunomodulatory mechanism at the material interfaces. [Biomaterials Advances] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| Scientists evaluated the role of lactate as an alternative mediator of MSC immunosuppressive properties and its contribution to the enhanced immunoregulatory activity of glycolytic MSCs. [Stem Cell Research & Therapy] |
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| Investigators performed epithelial-mesenchymal tissue recombination experiments using hair-forming back skin and glabrous plantar skin from mouse embryos to unveil that the back skin mesenchyme was inductive even before dermal condensate formation. [Development] |
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| Human MSC-derived exosomes were extracted by hypervelocity centrifugation method, and exosome morphology was observed by transmission electron microscopy, exosome diameter distribution was detected by particle size analysis, and exosome specific proteins were identified by Western blot. [Diabetology & Metabolic Syndrome] |
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| Hydrogel models of polymerized gelatin methacrylate were fabricated by using stereolithography and modified with hydroxyapatite via an alternate soaking process using a solution of calcium and phosphate ions. [ACS Biomaterials Science & Engineering] |
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| Researchers used adipose MSCs-derived exosomes for miR-218 delivery to breast cancer cells and evaluate miR-218 tumor-suppressing properties in vitro. [European Journal Of Medical Research] |
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| Bromodomain-containing protein 4 (BRD4) promoted human bone marrow MSCs osteogenic differentiation by inhibiting NF-κB pathway via enhancing WNT family members-4 (WNT4) expression. [Journal Of Orthopaedic Surgery And Research] |
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| Researchers explored therapeutic umbilical cord (UC)-MSC phenotypes for improving liver fibrosis. RNA-sequencing was used to analyze the response pattern of UC-MSCs after exposure to the serum of cirrhotic patients with HBV. [Journal Of Translational Medicine] |
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| Scientists analyzed the effects of tissue inflammation on the characteristics of MSCs. Human fat derived from the infrapatellar fat pad of knees with differing degrees of inflammation was extracted from specimens derived from total knee arthroplasties. [Stem Cell Research & Therapy] |
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| The authors highlight current challenges and potential future directions in the study of RNA modifications in MSCs, emphasizing the need for innovative tools to precisely map these modifications and decipher their context-specific effects. [Cell Death & Differentiation] |
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| Researchers from SMART, MIT’s research enterprise in Singapore have developed a groundbreaking technology capable of extracting MSCs directly from pure bone marrow without dilution. [Singapore-MIT Alliance for Research and Technology (SMART)] |
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| January 22 – 25, 2024 Santa Fe, New Mexico, United States |
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| University of California, Los Angeles – Los Angeles, California, United States |
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| Applied Stem Cell – Milpitas, California, United States |
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| German Cancer Research Center in the Helmholtz Association – Heideland, Germany |
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| University of California, Los Angeles – Los Angeles, California, United States |
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| China Pharmaceutical University – Nanjing, Jiangsu, China |
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