| Vol. 16.05 – 6 February, 2024 |
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| Investigators demonstrated that the adipocyte differentiation and immunomodulatory function of human adipose tissue-derived MSCs were mutually exclusive. [Molecular Therapy] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| Scientists investigated the protective effects of MSCs against severe acute pancreatitis-associated acute lung injury and its underlying mechanisms. They suggested that MSCs mitigate pathological injury, hemorrhage, inflammatory response in lung tissue, and cell damage in RLE-6TN cells. [European Journal Of Pharmacology] |
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| Researchers investigated the therapeutic effect of MSCs on airway remodeling in chronic asthma and explored the mechanisms by analyzing the polarization phenotype of macrophages in the lungs. [Inflammation] |
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| In vitro, human umbilical cord MSCs were cultured and induced to differentiate into neuron-like cells after they were pretreated with 150 μg/mL monosialoteterahexosyl ganglioside. [Experimental Cell Research] |
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| The osteoimmune microenvironment induced by calcium phosphate-coated polycaprolactone could not only enhance the osteogenic differentiation of bone marrow-derived MSCs in vitro but also promote the bone regeneration in vivo. [Journal Of Nanobiotechnology] |
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| Investigators explored the functional restoration and mechanism of human umbilical cord MSC exosomes on busulfan-induced injury in GC-1 spg cells and ICR mouse testes. [Ecotoxicology And Environmental Safety] |
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| Scientists investigated the biodistribution, homing and clearance of systemically administered human umbilical cord-MSCs in healthy BALB/c mice model. [Regenerative Therapy] |
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| Researchers explored the effects of ferroptosis and neutrophil extracellular traps and observed the therapeutic function of MSCs on sepsis-induced acute lung injury. [Peerj Life & Environment] |
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| Scientists investigated the synergistic effects of co-treating bone marrow MSCs with curcumin on vascular endothelial growth factor levels, in a rat model of myocardial ischemia (MI). [Molecular Biology Reports] |
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| The authors review the preclinical and clinical studies that have evaluated MSCs as a selective tumor delivery tool in various cancer therapy approaches, including gene therapy, immunotherapy, and chemotherapy. [Medicinal Research Reviews] |
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| Researchers highlighted the intricate interplay between PMNs and MSCs and their profound relevance in healthy and pathological conditions, shedding light on how to best strategize the use of MSCs in the expanding list of diseases with PMN involvement. [Stem Cells] |
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| The prestigious Dana-Farber Cancer Institute (DFCI) acknowledged that it would seek retractions for 6 papers and corrections for an additional 31 — some co-authored by DFCI chief executive Laurie Glimcher, chief operating officer William Hahn, and several other prominent cancer researchers. [Nature] |
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| February 26 – 27, 2024 Manipal, India |
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| Boston University – Boston, Massachusetts, United States |
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| University of Galway – Galway, Ireland, United Kingdom |
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| Karolinska Institutet – Solna, Sweden |
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| University of Alberta – Edmonton, Alberta, Canada |
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| Francis Crick Institute – London, England, United Kingdom |
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