| Vol. 16.12 – 2 April, 2024 |
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| Through assembling cell-laden modules, the macrophage-MSC, endothelial cell-MSC, and chondrocyte-MSC co-culture models were successfully established. [Advanced Materials] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| The authors developed the ‘Histology Analysis Pipeline.PY’ (HAPPY), a deep learning hierarchical method for quantifying the variability of cells and micro-anatomical tissue structures across placenta histology whole slide images. [Nature Communications] |
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| Investigators reported that a disordered region of inter SH2 domain contained AP2 binding motifs which could trigger clathrin and dynamin-mediated endocytosis independent of PI3K catalytic activity. [Nature Communications] |
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| Researchers investigated the efficacy of decellularized extracellular matrix derived from human dental pulp stem cells and gingival-derived mesenchymal stem cells as an inductive scaffold for osteogenic differentiation of gingival-derived mesenchymal stem cells. [Scientific Reports] |
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| The authors investigated the effect of electroactivity and electrical charge distribution on the biological response of human bone marrow stem cells cultured in monolayer on flat poly(vinylidene fluoride) substrates. [Heliyon] |
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| The lentiviral vectors zinc finger DHHC-type palmitoyl transferases 16 (ZDHHC16) or si-ZDHHC16 were introduced in the dental pulp stem cells and then the cells were induced by an odontogenic medium for 21 days. [BMC Oral Health] |
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| | Researchers postulated that MSCs could potentially suppress the pro-fibrotic activity of intrahepatic B cells, thereby inhibiting liver fibrosis progression. [Hepatology] |
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| Using a mouse model, in which repetitive low doses of streptozotocin induced a gentle, but progressive, hyperglycemia, investigators tested bone marrow-derived MSCs which were shown to be enriched with pro-angiogenic and immunomodulatory factors. [Stem Cells Translational Medicine] |
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| Scientists isolated and identified bone marrow-MSCs from ten primary multiple myeloma patients and ten healthy donors. [Cancer Cell International] |
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| Immune checkpoints and their ligands can be produced by MSCs and affect immune cell responses both through their secretion into the microenvironment or direct cell-to-cell interaction. [Biomarker Research] |
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| Investigators summarize recent advances in adipose-derived stem cell (ADSC) and their optimization strategies, including ADSC-derived exosomes, biomaterials, and genetic modifications. [Stem Cell Research & Therapy] |
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| Duke Health is part of a multi-institution research team receiving federal Advanced Research Projects Agency for Health funding to develop an osteoarthritis (OA) treatment that regenerates joints. [Duke University] |
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| University of Veterinary Medicine Vienna – Vienna, Austria |
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| University of Colorado – Aurora, Colorado, United States |
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| Dana-Farber Cancer Institute – Boston, Massachusetts, United States |
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| The University of Hong Kong – Hong Kong, Hong Kong |
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| King’s College London – London, England, United Kingdom |
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