Emily Salmini

Extracellular Matrix News

Boosting Functional Dental Pulp Regeneration by a Biomimetic Self-Assembling Hydrogel through Remodeling the Stem Cell Niche

[Acta Biomaterialia] Investigators developed an RQK-based strategy for functional dental pulp regeneration by integrating ECM-like architecture with instructive bioactive cues in a self-assembling hydrogel system.

Extracellular Matrix News

Cancer-Associated Fibroblasts: Origins, Functional Heterogeneity, and Therapeutic Potential

[Signal Transduction and Targeted Therapy] The authors dissect the multifaceted roles of cancer-associated fibroblasts, from their promotion of cancer cell proliferation, invasion, and angiogenesis through secreted factors and extensive ECM remodeling, to their profound influence on the immune landscape.

Muscle Cell News

Mount Sinai to Lead National Trial of Targeted Therapy for Infants With Noonan Syndrome and Severe Hypertrophic Cardiomyopathy

[Mount Sinai] Researchers at the Icahn School of Medicine at Mount Sinai will lead a new national clinical trial evaluating a precision medicine approach for infants with Noonan syndrome and related conditions who develop severe hypertrophic cardiomyopathy.

Muscle Cell News

IMMCG Researcher Receives $3.8 Million NIH Grant to Study Atherosclerosis

[Augusta University] Dr. Kunzhe Dong with the Immunology Center of Georgia, part of the Medical College of Georgia at Augusta University, has received a five-year, $3.8 million grant from the National Institutes of Health to study how a molecule in blood vessels may help protect against atherosclerosis.

Muscle Cell News

AFM-Telethon, Drew Weissman, and James Dowling Join Forces to Develop the Next Generation of Gene Therapies

[AFM-Telethon] AFM-Telethon is launching a two-year strategic research program with Drs. Drew Weissman and James Dowling. The aim is to develop lipid nanoparticles capable of targeting muscle tissue while minimizing uptake by the liver.

Muscle Cell News

Synergistic Promotion of Ferroptosis in Cardiomyocytes by Tumor Cell Secretory Factors and PD-1 Blockade

[Journal of Biochemical and Molecular Toxicology] Researchers hypothesized that PD-1 blockade–associated cardiotoxicity arises from a synergistic interaction between tumor cell secretory factors and immune checkpoint inhibition, culminating in ferroptotic cardiomyocyte death.

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FibroBiologics Announces Grant of European Patent for Fibroblast Delivery of Tumor Inhibitory Agents

[FibroBiologics, Inc.] FibroBiologics, Inc. announced that the European Patent Office has granted European Patent No. EP 4454709, titled "Fibroblast Delivery of Tumor Inhibitory Agents. The patent covers methods of preparing fibroblasts as anti-cancer delivery compositions by modifying the cells to improve their ability to home to cancer cells.

Applied Biologics Announces Full Enrollment of BIOxHEAL™ Phase III Sentinel Safety Cohort

[Applied Biologics, LLC.] Applied Biologics, LLC. announced the completion of enrollment into the sentinel safety cohort of its Phase III randomized controlled clinical trial evaluating BIOxHEAL^™ in patients with chronic, nonhealing diabetic foot ulcers.

StimLabs® Announces Commercial Launch of DermaForm™, a Uniquely Engineered Collagen Scaffold Particulate Device

[StimLabs ] StimLabs announced the commercial launch of DermaForm, an FDA 510(k)-cleared porcine-derived particulate collagen scaffold that manages a range of acute and chronic wounds.

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Emily Salmini

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