Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News
Cancer Stem Cell News
Cancer Stem Cell News is an online resource that curates the top research publications and reviews about cancer progenitor cells and cancer stem cells.
NIH Awards Younghye Song $2.5 Million to Study Metabolic Rewiring in Breast Tumor Innervation
[University of Arkansas] Younghye Song, assistant professor of biomedical engineering in the U of Arkansas's College of Engineering, has recently been awarded a $2.5 million National Institutes of Health R37 grant from the National Cancer Institute to investigate the role of metabolic rewiring in breast tumor innervation.
NIH Awards Younghye Song $2.5 Million to Study Metabolic Rewiring in Breast Tumor Innervation
Younghye Song, assistant professor of biomedical engineering in the U of Arkansas's College of Engineering, has recently been awarded a $2.5 million National Institutes...
GD2 and Its Biosynthetic Enzyme GD3 Synthase Promote Tumorigenesis in Prostate Cancer by Regulating Cancer Stem Cell Behavior
[Scientific Reports] Researchers showed that GD2 was expressed in a small subpopulation of prostate cancer cells in a subset of patients and a higher proportion of metastatic tumors.
Cancer Research Transformed by Landmark Gift to Queen’s University
[Queen's University] A transformational gift is set to significantly advance cancer research at Queen’s University. With support from Murray and Cara Sinclair, the university will build research capacity in an area of existing strength, establish advanced facilities, create training opportunities, and work to improve cancer care and treatments locally, nationally, and around the world.
NIH Wanted to Make Cancer Research More Diverse. The Effort Turned Out to Be a Costly Failure
[STAT News] The NCI’s Center for Cancer Research piloted a program of paying the travel costs for screening prospective research volunteers and, when needed, their caregivers, according to an internal NCI email obtained by STAT. NCI discontinued the pilot after one year, according to an NCI spokesperson.
A Developmental Constraint Model of Cancer Cell States and Tumor Heterogeneity
[Cell] Researchers posited a model by which cancer cell states are directly constrained by the organism's “developmental map.” According to this model, a population of cancer cells traverses the developmental map, thereby generating a heterogeneous set of states whose interactions underpin emergent tumor behavior.
The HHEX-ABI2/SLC17A9 Axis Induces Cancer Stem Cell-Like Properties and Tumorigenesis in HCC
[Journal of Translational Medicine] Investigators reported that HHEX was a novel CSCs target for hepatocellular carcinoma (HCC). They found that HHEX was overexpressed in HCC tissues and high expression of HHEX was associated with poor survival.
UCHL3 Induces Radiation Resistance and Acquisition of Mesenchymal Phenotypes by Deubiquitinating POLD4 in Glioma Stem Cells
[Cellular and Molecular Life Sciences] Expression and prognosis of the POLD family were analyzed in TCGA, the Chinese Glioma Genome Atlas and GEO datasets. Tumorsphere formation and in vitro limiting dilution assay were performed to investigate the effect of UCHL3-POLD4 on glioma stem cells self-renewal.
Cellular Origins and Lineage Plasticity in Cancer
[Cold Spring Harbor Perspectives In Medicine] The identity of cancer “cells-of-origin” has historically been a source of controversy across tumor types, as it has not been possible to witness the dynamic events giving rise to human tumors.
Stem-Cell States Converge in Multistage Cutaneous Squamous Cell Carcinoma Development
[Science] Investigators generated gene networks for a wide range of stem cell markers from hundreds of samples taken from normal skin, benign tumors, and malignant tumors, and visualized expression of these network metagenes in single cells derived from multiple stages of carcinogenesis.
Tumor Microenvironment-Induced FOXM1 Regulates Ovarian Cancer Stemness
[Cell Death & Disease] Researchers discovered that the pro-tumorigenic transcription factor FOXM1 is specifically induced by the microenvironment in ovarian cancer stem cells, through activation of FAK/YAP signaling.
The Transcriptional Landscape of Cancer Stem-Like Cell Functionality in Breast Cancer
[Journal of Translational Medicine] Investigators associated in vitro mammosphere formation assays with bulk tumor microarray profiling and deconvolution algorithms to map CSC functionality and the microenvironmental landscape in a large cohort of 125 breast tumors.
Cancer Stem Cell News consolidates the most recent publications covering research areas such as the identification and isolation of cancer stem cells, their proliferation and differentiation characteristics, gene expression and regulatory pathways, and the development of anti-cancer therapies. We also include cancer stem cell jobs and events hosted by leading research organizations, societies, and institutes.
