|
Vol. 11.04 – 2 February, 2022
|
|
|
|
|
|
The authors showed that reverse electron transfer through respiratory chain complex I was particularly active in brain CSCs. [Developmental Cell]
|
|
|
|
|
PUBLICATIONSRanked by the impact factor of the journal
|
|
|
|
|
Researchers developed a multimode nanoplatform to investigate tumor-initiating cancer stem cells, detected epigenetic changes, and subsequently explored their transformation signals following drug therapy.
[ACS Applied Materials & interfaces]
|
|
|
|
|
Scientists revealed that Hippo signaling effector YAP1 functioned as a key downstream regulator of LIN28 to modulate the CSC-like properties and tumor progressions in triple negative breast cancer.
[Oncogene]
|
|
|
|
|
The authors demonstrated that the N6-methyladenosine (m6A) reading protein YTHDF3 promoted the translation of the target transcript CTNNB1, contributing to ocular melanoma propagation and migration through m6A methylation.
[Oncogene]
|
|
|
|
|
Investigators demonstrated that hnRNP-E1 protein stability was increased upon ARIH1 silencing, whereas, overexpression of ARIH1 leads to a reduction in hnRNP-E1.
[Oncogene]
|
|
|
|
|
Scientists screened and verified the differential expression of circ_0001142 in breast cancer tissues and cell lines through bioinformatics and qRT-PCR.
[Pharmacological Research]
|
|
|
|
|
Researchers explored whether Mesenchymal stem cell- (MSC-) derived extracellular vesicles-delivered lipocalin-type prostaglandin D2 synthase (L-PGDS) could inhibit gastric cancer progression.
[Stem Cells International]
|
|
|
|
|
The authors investigated the association between the co-expression of SALL4/ALDH1A1 proteins and clinicopathological parameters and their prognostic value in serous ovarian carcinoma patients using immunohistochemical staining on tissue microarrays. [Journal of Ovarian Research]
|
|
|
|
|
Researchers determined live cell metabolism and bioenergetics in pathophysiological relevant, WNT-dependent glioblastoma stem cell models.
[Frontiers in Bioscience-Landmark]
|
|
|
|
|
Using flow cytometry and western blot assays, the authors have demonstrated that programmed cell death ligand 1 expression is higher in endometrial cancer stem-like cell derived from endometrial cancer than in nonstem-like cancer cells. [Frontiers in Bioscience-Landmark]
|
|
|
|
|
|
Scientists provide a comprehensive review of clinical significance of mesenchymal circulating tumor cells in breast cancer together with statistical analysis of previously published data.
[Cellular and Molecular Life Sciences]
|
|
|
|
|
The authors review leukemia stem cell biology, particularly as it relates to the very heterogeneous nature of acute myeloid leukemia and to its high disease relapse rate. [Stem Cell Reviews and Reports]
|
|
|
|
|
|
The Lung Cancer Research Foundation (LCRF) and KRAS Kickers announced a partnership aimed at raising much needed funds for research. Together they to pledge to fund at least one two-year grant in 2022 with the goal of improving outcomes for people with KRAS-mutant lung cancer.
[Lung Cancer Research Foundation]
|
|
|
|
|
Panbela Therapeutics, Inc. announced the initiation of the company’s global Phase II clinical trial of SBP-101 in combination with Gemcitabine and Nab-Paclitaxel in patients with metastatic pancreatic ductal adenocarcinoma, which is referred to as the ASPIRE trial. [Panbela Therapeutics, Inc.]
|
|
|
|
|
|
March 9 – 11, 2022 Melbourne, Victoria, Australia
|
|
|
|
|
|
|
Knight Cancer Institute – Portland, Oregon, United States
|
|
|
|
|
Albert Einstein College of Medicine – Bronx, New York, United States
|
|
|
|
|
Albert Einstein College of Medicine – Bronx, New York, United States
|
|
|
|
|
Moffit Cancer Center – Tampa Bay, Florida, United States
|
|
|
|
|
Luxembourg Institute of Health – Luxembourg, Luxembourg
|
|
|
|
|