 | | Vol. 11.06 – 16 February, 2022 |
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| The authors showed that Fusobacterium nucleatum promoted colorectal cancer stem-like cells (CCSCs) self-renewal, and non-CCSCs to acquire CCSC features by manipulating cellular lipid accumulation.
[Advanced Science] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| Researchers uncovered a subpopulation of cells labeled as CD45−EPCAM+PROCR+ in nasopharyngeal carcinoma biopsy samples that exhibited stem cell-like characteristics.
[Signal Transduction and Targeted Therapy] |
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| Scientists interrogated the role of adenosine-to-Inosine RNA editing mediated by adenosine deaminase acting on RNA1 (ADAR1) in glioblastoma stem cells and found that both ADAR1 and global RNA editomes were elevated in glioblastoma stem cell compared to normal neural stem cells.
[Journal of Clinical Investigation] |
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| Researchers showed that reverse electron transfer through respiratory chain complex I was particularly active in brain cancer stem cells.
[Developmental Cell] |
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| Genetically engineered and xenograft tumor models were used to explore the effect of interferon-induced protein with tetratricopeptide repeat 2 (IFIT2) -depleted metastatic oral squamous cell carcinoma on cancer cachexia.
[Journal of Cachexia Sarcopenia and Muscle] |
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| Scientists reported that tumor suppressor candidate 2 (TUSC2) protein expression was reduced/lost in glioblastoma compared to normal brain due to protein destabilization.
[Cancer Letters] |
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| Researchers designed a CD34/CD3 bispecific T-cell engager (BiTE) and characterized its anti-leukemia potential in vitro, ex vivo and in vivo.
[Haematologica] |
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| The authors isolated extracellular microparticles derived from apoptotic hepatic progenitor cells and tested their ability to inhibit hepatocarcinogenesis.
[Journal of Nanobiotechnology] |
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| Scientists addressed the relevance of 3D organoid technology to investigate the biological effects of cold atmospheric plasma on normal epithelial stem cells and tumor cells isolated from mouse small intestine.
[Cell Death Discovery] |
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| The authors highlight potential adverse effects of accumulative combination, and further point out future direction in optimization of combination, including targeting post-translational modification of PD-(L)1 and improving precision of treatment.
[Journal of Experimental & Clinical Cancer Research] |
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| BriaCell Therapeutics Corp. announced the appointment of Giuseppe Del Priore, MD, MPH, as the Company’s Chief Medical Officer.
[BriaCell Therapeutics, Corp.] |
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| March 20 – March 25
Vienna, Austria |
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| | Icahn School of Medicine at Mount Sinai – New York, New York, United States |
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| Babraham Institute – Babraham, Cambridgeshire, United Kingdom |
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| | Albert Einstein College of Medicine – Bronx, New York, United States |
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| | Albert Einstein College of Medicine – Bronx, New York, United States |
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| | Moffit Cancer Center – Tampa Bay, Florida, United States |
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