 | | Vol. 11.13 – 6 April, 2022 |
| |
|
|
| Researchers identified fusions from as little as two unstained slides of FFPE tumor biopsy tissue, from circulating tumor cells collected from tumor-bearing mice, and from liquid biopsy samples from patients with known fusion-positive cancers.
[Modern Pathology] |
|  |
|
|
| PUBLICATIONSRanked by the impact factor of the journal |
|
|
|
| Scientists investigated signaling cascades of B cell lymphoma 6 (BCL6) in the CSC compartment of triple negative breast cancers, and the mechanisms that govern its activity, mainly through Notch signaling.
[Cellular Oncology] |
|
|
|
| Sphaerococcenol A capacity to impact colorectal-CSCs tumorspheres was evaluated by determining tumorspheres viability, number, and area, as well as the proteasome inhibitory activity.
[Biomedicine & Pharmacotherapy] |
|
|
|
| Enrichment of cancer stem cells was observed in neurospheres by FACS using CD133 antibody and RT-PCR.
[Frontiers in Pharmacology] |
|
|
|
| Using MRI, scientists determined the correlation between glutamine uptake and the distribution of glutamine transporters, namely ASCT2 and SLC38A2, glutaminase, and CSC markers, such as CD44 and CD166, in a mouse xenograft model of HT29 human colorectal cancer cells.
[Scientific Reports] |
|
|
|
| Investigators showed that miR-145-5p, a recently discovered miRNA, was expressed at low levels in primary glioma stem cells.
[Journal of Cancer] |
|
|
|
| Scientists investigated the effects of miR-222-3p on the formation of medulloblastoma stem-like cells via the Notch2/c-myc pathway.
[Immunopharmacology and Immunotoxicology] |
|
|
|
| Significant genes associated hepatocellular carcinoma stemness features were screened through weighted gene co-expression network analysis and were functionally annotated using enrichment analysis.
[Critical Reviews in Eukaryotic Gene Expression] |
|
|
|
| Investigators constructed and characterized human epidermal growth factor receptor 2 (HER2) lipid magnetic ball for separating circulating tumor cells in patients with gastric carcinoma.
[Molecular Medicine Reports] |
|
|
|
|
| Scientists discuss in detail the divergence of early metastases as circulating tumor cells and the involvement of miRNAs as detectable blood-based diagnostic biomarkers that warrant a timely screening of cancer.
[Molecular Cancer] |
|
|
|
| The authors summarize the recent advances in cancer pathological roles and mechanisms of RNA-binding proteins (RBPs) in regulating mRNA stability and translation with an emphasis on the emerging category of RNA modification-associated RBPs.
[Seminars in Cancer Biology] |
|
|
|
|
| The FDA approved axicabtagene ciloleucel for adult patients with large B-cell lymphoma that is refractory to first-line chemoimmunotherapy or relapses within 12 months of first-line chemoimmunotherapy.
[US FDA] |
|
|
|
| Two researchers at the University of Toronto and its hospital partners – one a stem cell biologist, the other a global health researcher – have been honoured with 2022 Canada Gairdner Awards, the country’s most prestigious awards for medical and health science.
[University of Toronto] |
|
|
|
|
| May 1 – 5, 2022
Riviera Maya, Mexico |
|
|
|
|
|
| | The University of Hong Kong – Hong Kong, China |
|
|
|
| Luxembourg Institute of Health – Strassen, Luxembourg |
|
|
|
| | CRUK Manchester Institute – Manchester, England, United Kingdom |
|
|
|
| | Genentech, Inc. – South San Francisco, California, United States |
|
|
|
| | Gilead Sciences – Foster City, California, United States |
|
|
|
|
Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News
Umbilical & Placental Cell News
