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Vol. 12.03 – 25 January, 2023
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Investigators reported that YTX-7739 triggered lipotoxicity in patient-derived glioblastoma stem-like cells (GSCs) and inhibited fatty acid desaturation in GSCs orthotopically implanted in mice.
[Science Translational Medicine]
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PUBLICATIONSRanked by the impact factor of the journal
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Researchers demonstrated the feasibility of the norbornene amino acid on ubiquitin strategy by identifying and validating substrates of linear ubiquitination in patient-derived glioblastoma stem-like cells.
[Nucleic Acids Research]
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Scientists showed that reduction and inactivation of Ran GTPase-activating protein 1 (RanGAP1) commonly occured in human osteosarcoma, which was associated with a high rate of chromothripsis.
[Developmental Cell]
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The authors leveraged the WAP-T syngeneic mammary carcinoma mouse model and developed a strategy combining magnetic-activated cell sorting-based tumor cell enrichment with high-throughput transcriptome analyses.
[International Journal of Cancer]
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Scientists found that the cell viability and half-maximal inhibitory concentration of glioma stem cells (GSCs) against temozolomide significantly decreased after GSCs underwent serum-induced differentiation to adherent growth of tumor cells.
[Cell Death Discovery]
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The effects of tetrandrine on cell growth, cell viability, cell stemness capacity, cell migration, and cell invasion, as well as the molecules involved in these processes, were investigated in a cell culture system.
[American Journal Of Chinese Medicine]
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Researchers verified the potency of GO-Y030 against a CSC population and observed that GO-Y030 suppressed CSC sphere-forming ability in several cancer cell lines.
[FEBS Open Bio]
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Scientists observed elevated myxoprotein 1 (MUC1) in osteosarcoma and a depressed prognosis in patients with high MUC1 expression profiles.
[Pathology Research And Practice]
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Investigators have established an enzyme-free, easy-to-operate, and non-disruptive method for detecting circulating tumor cells in blood circulation based on the dual-toehold accelerated catalytic hairpin assembly strategy.
[Microchimica Acta]
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The authors focus on discussing recent discoveries addressing the roles of histone modifiers and noncoding RNAs and the mechanisms of their interactions in gastric tumorigenesis.
[Experimental & Molecular Medicine]
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Scientists propose a monophyletic origin of cancer model which suggests that CSCs are stem cells that lose control of differentiation.
[Stem Cell Reviews and Reports]
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The Damon Runyon Cancer Research Foundation has announced eight recipients of the 2023 Damon Runyon-Rachleff Innovation Award, established to support “high-risk, high-reward” ideas with the potential to significantly impact the prevention, diagnosis, or treatment of cancer.
[Damon Runyon Cancer Research Foundation]
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Dr. Gabor Tigyi of the University of Tennessee Health Science Center was announced as the recipient of the 2022 Dénes Gábor Prize for scientific innovation.
[The University of Tennessee Health Science Center]
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April 17 – 19, 2023
Freiburg im Breisgau, Germany
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University of Bergen – Bergen, Norway
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Michigan State University – East Lansing, Michigan, United States
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Imperial College London – London, United Kingdom
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IRCCS Candiolo Cancer Institute – Turin, Italy
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Cancer Research Center of Lyon – Lyon, France
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Cancer Stem Cell News
Cell Therapy News
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