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Vol. 12.34 – 30 August, 2023
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Scientists showed that netrin-1 was an independent prognostic marker for the clinical progression of breast and ovary cancers. They found a significant correlation between netrin-1 expression and CSC marker levels. [Cell Death & Differentiation]
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PUBLICATIONSRanked by the impact factor of the journal
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Researchers presented evidence that lengsin, lens protein with glutamine synthetase domain (LGSN), was overexpressed in gastric CSCs and was highly correlated with malignant progression and poor survival in gastric cancer patients.
[Cell Death & Disease]
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The expressions and clinicopathological characteristics of SAM pointed domain containing ETS transcription factor (SPDEF) in luminal breast cancer patients were evaluated bioinformatically.
[Cell Death & Disease]
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Investigators determined the effects of FOSL1 on glioma stem cell markers CD133 and ALDH1 by flow cytometry and the maintenance of stem cell activity by extreme limiting dilution assays.
[Cellular And Molecular Life Sciences]
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The authors found that overexpression of WNT2 enhanced stemness properties to promote chemoresistance and tumorigenicity in gastric CSCs.
[Oncogene]
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The mRNA and protein expression were tested by qRT-PCR and Western blot, respectively. ChIP assay was performed to detect SRY-box transcription factor 2 enrichment on the Pleckstrin Homology Like Domain Family B Member 2 promoter.
[Annals of Clinical and Translational Neurology]
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Scientists showed for the first time that nanomolar concentration of bisphenol A could markedly increase the formation and expansion of ovarian CSCs concomitant.
[Journal Of Cellular And Molecular Medicine]
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Colorectal CSCs were enriched in standard serum-free medium and serum-free medium with different concentrations of serum for one week.
[Discover Oncology]
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Investigators identified the mechanisms of tumorigenicity in CD13+CD166− cells. They compared gene expression profiles of CD13+CD166− cells with other cell sub-populations and identified nine overexpressed genes.
[Human Cell]
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Researchers investigated the role of programmed death-ligand 1 (PD-L1) in esophageal CSC (ECSC) formation. ECSCs were enriched and characterized using various assays. [Environmental Toxicology]
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The authors discuss various molecular mechanisms by which adipocytes regulate CSCs, including secretion of adipokines, extracellular matrix production, biosynthesis of estrogen, metabolism, and exosome. [Cancer Science]
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Two teams of UBC researchers have received $4.8 million to advance cancer research from the 2023 Terry Fox New Frontiers Program Project Grant competition.
[University of British Columbia]
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The US government has extended for six months a key symbolic agreement to cooperate with China in science and technology. [Nature]
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October 12 – 13, 2023 Singapore & Virtual
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National Cancer Institute – Bethesda, Maryland, United States
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Cedars-Sinai – Los Angeles, California, United States
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National Cancer Institute – Bethesda, Maryland, United States
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Cedars-Sinai – Los Angeles, California, United States
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SciLifeLab – Solna, Sweden
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