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Vol. 12.36 – 13 September, 2023
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Researchers established gelatin-based 3D biomimetic scaffolds mimicking the stiffness and collagen content of esophageal squamous cell carcinoma (ESCC), which could enrich ESCC CSCs efficiently.
[Biomaterials]
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PUBLICATIONSRanked by the impact factor of the journal
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The authors investigated nimbolide, a limonoid triterpenoid that has potent anticancer properties but poor pharmacokinetics and low bioavailability limit its therapeutic application.
[Molecular Therapy-Nucleic Acids]
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Scientists revealed the molecular mechanism of the CSCs marker gene C-X-C chemokine receptor type 4 (CXCR4) in gastric cancer growth and metastasis through scRNA-seq combined with bulk RNA-seq.
[npj Precision Oncology]
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Immunohistochemical staining was used to evaluate β-1,4-N-Acetyl-Galactosaminyltransferase 1 (B4GALNT1) expression in hepatocellular carcinoma tissues and adjacent normal liver tissues.
[JHEP Reports]
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Four machine learning methods were used to construct and validate a stemness subtype classification model, and cell function experiments were performed to verify the effect of the signature gene ARTN on non-small cell lung cancer.
[Stem Cell Research & Therapy]
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Neural precursor cell-expressed developmentally down-regulated protein 8 was identified to be conjugated to lysine-specific demethylase 1 (LSD1) at K63 by ubiquitin-conjugating enzyme E2 M.
[International Journal of Biological Macromolecules]
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Investigators reported a new approach based on dual-isotope inductively coupled plasma quadrupole mass spectrometry (ICP-QMS) for single cell phenotypic analysis.
[Analytical Chemistry]
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Researchers used miRNA-seq technology to screen out the highly expressed miR-372-5p among the miRNAs differentially expressed in plasma exosomes of clinical colorectal cancer (CRC) patients.
[Cellular Signalling]
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Gene set enrichment analysis and immunohistochemistry were performed to establish the correlation between histone lysine demethylase 6A (KDM6A)/lysin methyltransferase 2B (KMT2B) and CSC stemness.
[Translational Oncology]
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MCF-7 and MDA-MBA-231 breast cancer cells (BCCs) were cultured in suspension and adherent. The effect of suspension state on BCCs was further elucidated by observing suspension cell clusters, sorting CD44+/CD24– cell subpopulation, and detecting self-renewal ability.
[Tissue and Cell]
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The authors review the targeting of CSCs by immunotherapy strategies such as dendritic cell vaccines, chimeric antigen receptors-engineered immune cells, natural killer-cell therapy, monoclonal antibodies, and more.
[Cancer Medicine]
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Moderna, Inc. and Immatics N.V. announced a strategic research and development collaboration to pioneer novel and transformative therapies for cancer patients with high unmet medical need.
[Immatics]
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The National Cancer Institute has awarded the Icahn School of Medicine at Mount Sinai a $3.4 million grant to create a model that identifies the best prostate cancer treatment for people with HIV.
[Mount Sinai]
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October 19 – 22, 2023
Minneapolis, Minnesota, United States
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Chinese Academy of Sciences – Shanghai, China
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Northwestern University – Chicago, Illinois, United States
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Dana-Farber Cancer Institute – Boston, Massachusetts, United States
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University of South Australia – Adelaide, Australia
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Creative Biolabs – New York, New York, United States
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Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News
Umbilical & Placental Cell News