 | | Vol. 12.41 – 8 November, 2023 |
| |
|
|
| The authors examined the metabolic adaptations of metastasis-initiating cells in female breast cancer and how those shape their metastatic phenotype.
[Nature Communications] |
|
|
|
 | | PUBLICATIONSRanked by the impact factor of the journal |
|
|
|
| Researchers used the PAX5::ELN oncogenic model to demonstrate a causal link between the differentiation blockade, the self-renewal, and the emergence of pre-leukemic stem cells.
[Journal of Experimental Medicine] |
|
|
|
| Scientists developed a nebulized nanocatalytic medicine strategy in which iron-based nanoparticle-regulated tumor-associated macrophages effectively target CSC niches and trigger CSC ferroptosis in the early stage of lung cancer.
[Journal Of The American Chemical Society] |
|
|
|
| Biopsy and derived-glioblastoma stem-like cell (GSC) characterization revealed a FLAIR/CNI+ sample enrichment in GSC and in gene signatures related to stemness, DNA repair, adhesion/migration, and mitochondrial bioenergetics.
[Science Advances] |
|
|
|
| Scientists found that high Claudin-1 expression in colorectal cancer was associated with cancer stemness and chemoresistance signaling pathways in patient datasets, and it promotes chemoresistance both in vitro and in vivo.
[Cancer Letters] |
|
|
|
| The authors used single cell RNA sequence technology to identify the characteristic of CSCs. They found that the lung adenocarcinoma cancer stem population was highly inflammatory and remodeled the tumor microenvironment.
[Cell Death & Disease] |
|
|
|
| Scientists reported a combined in vitro/in vivo genome-wide CRISPR synthetic lethality screening approach in a relevant triple-negative breast cancer cell line model to identify several targets responsible for the chemotherapy drug, paclitaxel resistance.
[Oncogenesis] |
|
|
|
| Investigators characterized feed-forward regulation of leukemia inhibitory factor receptor (LIFR) expression in response to FAM3C/LIFR/STAT3 signaling in mammary epithelial cells.
[Cancer Biology & Therapy] |
|
|
|
| Researchers evaluated the antineoplastic effects of Nanog inhibition, a critical transcription factor associated with pluripotency and its role in ovarian cancer tumorigenesis, using the novel therapeutic agent Amcasertib in ovarian cancer cells.
[Medical Oncology] |
|
|
|
|
| Investigators explored novel avenues of research that delve into the distinctive characteristics of CSCs within their surrounding tumor microenvironment.
[Stem Cell Reviews And Reports] |
|
|
|
|
| Dr. Deborah Lang has been awarded a two-year, $300,000 Discovery Boost Grant from the American Cancer Society for her research project “Exploring roles for PAX3 in regulating gene expression on a post-transcriptional level.”
[Boston University] |
|
|
|
|
| December 4 – 6, 2023
Vienna, Austria |
|
|
|
|
|
| | The Ohio State University – Columbus, Ohio, United States |
|
|
|
| | Danish Cancer Society – Copenhagen, Hovedstaden |
|
|
|
| | Baylor College of Medicine – Houston, Texas, United States |
|
|
|
| | Cedars-Sinai – Los Angeles, California, United States |
|
|
|
| | Fred Hutchinson Cancer Center – Seattle, Washington, United States |
|
|
|
|
Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News
