| Vol. 12.42 – 15 November, 2023 |
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| Scientists applied ultrasensitive circulating tumor DNA sequencing to 146 plasma and cerebrospinal fluid samples from 67 patients, to develop an entirely noninvasive dynamic risk model considering clinical and molecular features of central nervous system lymphoma. [Blood] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| Researchers identified one of the requirements for tumor-initiating cells in immunocompetent animals. In addition, they have showed that tumor growth could be inhibited by externally administered nicotinamide mononucleotide against macrophage senescence-like state. [Journal For Immunotherapy Of Cancer] |
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| In leukemic stem cell (LSC) models, the extended dose of azacitidine induced differentiation and depleted CD34+CD38– LSCs. [Haematologica] |
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| Functional analysis showed that MIR31HG fostered stemness-associated malignant features of non-small cell lung cancer cells. [Oncogene] |
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| Researchers indicated that endoplasmic reticulum‑mitochondrial homeostasis was essential for regulation of glioma initiating cells glucose metabolism and survival. [International Journal of Oncology] |
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| Scientists reported, for the first time, the expression profile of the Orai family members, Orai1-3, and different TRPC channels, TRPC1, 3 and 6, in breast CSCs. [Scientific Reports] |
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| Investigators showed that aberrant SET-domain-containing protein 5 (SETD5) overexpression induced stemness in colorectal cancer cells. [Scientific Reports] |
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| The authors revealed a novel function of TAB182 as a potential negative regulator of cancer stem-like properties and drug sensitivity in triple-negative breast cancer cells. [BMC Cancer] |
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| Scientists determined that CircZNF800 was an oncogenic factor that regulated CSC properties which led to colorectal tumorigenesis. [BMC Cancer] |
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| The authors describe viral-based and CRISPR-Cas9-based cellular barcoding, lineage tracing, and imaging-based approaches. [Cancer and Metastasis Reviews] |
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| Memorial Sloan Kettering Cancer Center has announced three innovative investigators as the recipients of this year’s Paul Marks Prize for Cancer Research. [Memorial Sloan Kettering Cancer Center] |
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| December 5 – 9, 2023 San Antonio, Texas, United States |
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| German Cancer Research Center in the Helmholtz Association – Heideland, Germany |
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| NIH National Cancer Institute – Bethesda, Maryland, United States |
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| The Ohio State University – Columbus, Ohio, United States |
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| Danish Cancer Society – Copenhagen, Hovedstaden |
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| Baylor College of Medicine – Houston, Texas, United States |
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