| Vol. 13.01 – 16 January, 2024 |
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Flow cytometry was used to sort and analyze bladder cancer stem cells. Tumor sphere formation, soft agar colony formation assay, EdU assay, apoptosis analysis, cell viability, and cisplatin sensitivity assay were used to investigate the functional roles of LASS2. [BMC Medicine] |
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PUBLICATIONSRanked by the impact factor of the journal |
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| Data from The Cancer Genome Atlas suggests a correlation between high EXOSC5 mRNA expression and unfavorable endometrial carcinoma prognosis. [International Journal Of Biological Sciences] |
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| Scientists reported that M2-type tumor-associated macrophages contributed to cancer stemness in triple-negative breast cancer cells via the secretion of VEGFA. [International Journal Of Biological Sciences] |
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| Five novel cell lines were obtained from patient-derived biopsies of mucosal melanomas (MM) arising in the sino-nasal mucosa and designated as SN-MM1-5. The morphology, ultrastructure and melanocytic identity of SN-MM cell lines were validated by transmission electron microscopy and immunohistochemistry. [Journal Of Translational Medicine] |
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| The authors reported that nicotine enhanced hepatocellular carcinoma cancer stemness and malignant progression by upregulating the expression of GC-rich binding factor 2 (GCF2) and subsequently activating the Wnt/ꞵ-catenin/SOX2 signaling pathway. [Ecotoxicology and Environmental Safety] |
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| Investigators identified an upregulation of lncRNA FOXD1-AS1 in CSCs. The enforced expression of lncRNA FOXD1-AS1 promotes tumorigenesis and self-renewal in pancreatic cancer CSCs. [Cancer Cell International] |
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| Researchers probed the mechanism of hypoxia-treated cancer-associated fibroblasts regulating cell stemness and gemcitabine resistance in pancreatic cancer. [Molecular Carcinogenesis] |
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| Scientists elucidated the transcriptomic disparities between mammospheres of MCF-7 and T47D cells using bioinformatics analyses of differentially expressed genes. [Heliyon] |
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| Investigators observed that leukemia inhibitory factor could increase the spheroid formation and stemness marker expression in colorectal cancer cell lines, such as HCT116 and Caco2 cells. [Biochemical Genetics] |
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| Scientists review the similarities between tissue repair and carcinogenesis, with a special focus on the epigenetic mechanisms activated by cells during repair and opted by carcinoma cells in multiple epithelia. [Cell Death & Differentiation] |
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| The authors consolidate the latest findings on CSCs biomarkers, targeted agents as well as biomarkers associated signaling pathways in well-established cancer types, thereby contributing to improved prognostic outcomes. [Journal Of Drug Targeting] |
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| Until now, Tecentriq has been given directly into patients’ veins by IV infusion which takes approximately 30-60 minutes. The new subcutaneous injection will cut treatment time to approximately seven minutes, with most injections taking between four and eight minutes. [Roche] |
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| It was announced that researchers at UCLA Health Jonsson Comprehensive Cancer Center received two grants totaling $9.1 million from the National Cancer Institute to advance liquid biopsy technologies for the early detection of cancer. [Los Angeles Business Journal] |
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| March 10 – 12, 2024 Miami, Florida, United States & Virtual |
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| Karolinska Institutet – Solna, Sweden |
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| The Francis Crick Institute – London, England, United Kingdom |
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| City of Hope – Duarte, California, United States |
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| MD Anderson Cancer Center – Houston, Texas, United States |
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| City of Hope – Duarte, California, United States |
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