 | | Vol. 13.03 – 24 January, 2024 |
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| Using preclinical mouse and human-derived models, investigators found low intermittent doses of 6-Thio-2’-deoxyguanosine inhibit tumor growth and reduce metastatic burden.
[Nature Communications] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| Scientists demonstrated that the regulatory programs of quiescent leukemic stem cell (LSC) in chronic phase chronic myeloid leukemia (CML) are similar to that of embryonic stem cells, pointing to a role for wild type p53 in LSC self-renewal.
[Nature Communications] |
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| Researchers conducted a retrospective analysis of the multicenter prospective PROPHECY trial of metastatic castration-resistant prostate cancer men treated with abiraterone/enzalutamide.
[Clinical Cancer Research] |
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| The authors evaluated the clinical significance of YTHDF1 using human hepatocellular carcinoma (HCC) samples and found that YTHDF1 was significantly upregulated in HCCs with high stemness scores and was positively associated with recurrence and poor prognosis.
[Cancer Research] |
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| GFP-labeled tumor cells were sorted from invasive and non-invasive regions within co-cultures. Ui-RNA sequencing analysis was performed to find a gene cluster up-regulated in the invasive compartment.
[Journal of Experimental & Clinical Cancer Research] |
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| Ninety-seven patients with hormone receptor-positive metastatic breast cancer were prospectively enrolled during standard treatment at Samsung Medical Center.
[Breast Cancer Research] |
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| The effect of mind bomb 1 (MIB1) on peritoneal metastasis of gastric cancer was confirmed in vitro and in vivo. Co-immunoprecipitation and mass spectrometry demonstrated the association between MIB1 and DEAD-box helicase 3 X-linked (DDX3X).
[Gastric Cancer] |
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| Bioinformatic analyses of The Cancer Genome Atlas data were performed, and the association of alkB homolog 5 (ALKBH5) in predicting overall survival in patients with intrahepatic cholangiocarcinoma was investigated.
[Translational Oncology] |
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| Single-cell RNA sequencing of CD45-negative cell fraction of breast cancer patients was performed. All circulating tumor cells were divided into nine groups according to their integrin profile.
[PeerJ] |
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| The mutual interactions between CSCs and cancer niche immune cells are largely uncharacterized. The authors focus on colorectal CSCs, CSC-immune cell interactions, and CSC-based immunotherapy.
[Experimental Hematology & Oncology] |
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| Dr. Tara Horrill and Dr. Joel Pearson at the Rady Faculty of Health Sciences were among the winners of the Canadian Cancer Society’s 2023 Emerging Scholar Research Grants competition.
[University of Manitoba] |
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| Renowned immunologist E. John Wherry, PhD, and distinguished pediatric oncologist John M. Maris, MD, have been named as members of the 2024 class of fellows of the American Association for Cancer Research (AACR) Academy.
[University of Pennsylvania] |
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| February 27 – 28, 2024
London, England, United Kingdom |
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| | Thomas Jefferson University – Philadelphia, Pennsylvania, United States |
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| | Human Technopole – Milan, Italy |
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| | MD Anderson Cancer Center – Houston, Texas, United States |
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| | Karolinska Institutet – Solna, Sweden |
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| | University of Birmingham – Birmingham, England, United Kingdom |
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