Cord Blood Proficiency Testing: Standardize your Hematopoietic Colony-forming Cell (CFC) Assays with the PT Program.
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Wisconsin Team Grows Retina Cells from Skin-derived Stem Cells
A team of scientists has successfully grown multiple types of retina cells from two types of stem cells — suggesting a future in which damaged retinas could be repaired by cells grown from the patient’s own skin. [University of Wisconsin-Madison, Madison]
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Finnish Scientists Discover Nerve Growth Factor with Possible Therapeutic Potential in Parkinson’s Disease
Researchers report that their latest results show a certain growth factor can be used to halt the progress of damage brought on by a nerve poison and possibly even restore the function of damaged cells. [Academy of Finland, Helsinki]
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‘Glow in the dark’ Red Blood Cells Made from Human Stem Cells
Victorian stem cell scientists from Monash University have modified a human embryonic stem cell line to glow red when the stem cells become red blood cells. [Monash University, Victoria]
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Improvement of Liver Stem Cell Engraftment by Protein Delivery
European researchers have engineered a chimeric protein that increases cell survival, migration and proliferation to improve stem cell engraftment. [INSERM, Paris]
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BrainStorm Cell Therapeutics Secures Funding to Reach Clinical Trials for ALS
BrainStorm Cell Therapeutics Inc. announced recently that the company has secured the funding required to complete pre-clinical trials underway for the treatment of Amyotrophic Lateral Sclerosis. [BrainStorm Cell Therapeutics, New York]
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Scientists Develop Gene Therapy Method to Prevent Some Inherited Diseases
Researchers believe they have developed one of the first forms of genetic therapy – a therapy aimed at preventing serious diseases in unborn children through mutated DNA in cell mitochondria. [Oregon Health and Science University, Portland]
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ABSTRACTS, REVIEWS AND SPECIAL REPORTS
Repopulation Efficiencies of Adult Hepatocytes, Fetal Liver Progenitor Cells, and Embryonic Stem Cell-Derived Hepatic Cells in Albumin-Promoter-Enhancer Urokinase-Type Plasminogen Activator Mice
This study explores the relative capacity of fetal liver progenitor cell suspensions and hepatic precursor cells derived from embryonic stem cells to engraft and repopulate a recipient liver compared with adult hepatocytes. [The American Journal of Pathology]
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Regeneration of Intestinal Stem/Progenitor Cells Following Doxorubicin Treatment of Mice
Here, the researchers investigated the factors involved with the rapid turnover of cells fed by a hierarchy of transit amplifying and stem/progenitor cells destined to give rise to the four differentiated epithelial lineages of the small intestine. [American Journal of Physiology – Gastrointestinal Liver Physiology]
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NFI-A Directs the Fate of Hematopoietic Progenitors to the Erythroid or Granulocytic Lineage and Controls {Beta}-globin and G-CSF Receptor Expression
This paper shows that in normal human hematopoiesis the transcription factor nuclear factor I-A exhibits a marked lineage-specific expression pattern: it is upmodulated in the erythroid lineage while fully suppressed in the granulopoietic series. [Blood]
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Definitive Proof for Direct Reprogramming of Hematopoietic Cells to Pluripotency
This paper shows definitive proof of direct reprogramming of murine hematopoietic cells with no rearranged genes. [Blood]
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