Webinar: Feeder-independent growth of hESCs & hiPSCs using TeSR(TM)2
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VIDEO: Introducing TeSR2 medium for feeder-free, animal protein-free culture of human ESCs and iPSCs
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Nanomagnet in “Star-Trek Style” Wand Could Cure Cancer
For reasons scientists do not fully understand, stem cells have an affinity for cancer and are exploiting this property in bone marrow ”mesenchymal” stem cells to deliver the iron oxide particles.
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How Hematopoietic Stem Cell Development Is Regulated
During cell division, whether hematopoietic stem cells will develop into new stem cells or differentiate into other blood cells depends on a chemical process called DNA methylation. [Max Delbruck Center for Molecular Medicine, Berlin]
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And the Beat Goes On: Scientists Jump-start the Heart by Gene Transfer
Recent research shows that gene therapy may be used to improve an ailing heart’s ability to contract properly. [Universities of Michigan, Ann Arbor]
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Novel Polymer Delivers Genetic Medicine, Allows Tracking
Researchers have developed a new molecule that can travel into cells, deliver genetic cargo, and packs a beacon so scientists can follow its movements in living systems. [Virginia Tech, Blacksburg]
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Research Reveals Unique Properties of Vitro’s Fluorescent Stem Cells
Vitro Diagnostics, Inc. announced completion of a research report concerning its fluorescent stem cells involving transfer of fluorescent to differentiated cells. [Vitro Diagnostics, Inc., Golden]
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Major Improvements Made In Engineering Heart Repair Patches from Stem Cells
Researchers have succeeded in engineering human tissue patches free of some problems that have stymied stem-cell repair for damaged hearts. [University of Washington, Seattle]
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Stem Cells Which “Fool Immune System” May Provide Vaccination for Cancer
By immunizing the host with stem cells, the researchers are able to ‘fool’ the immune system to believe that cancer cells are present and thus to initiate a tumor-combating immune program. [UConn Stem Cell Institute, Farmington]
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Scientists Announce Potential Stem Cell Alternative to Live Animal Testing for Corneal Damage
Initial results using non-animal or “in vitro” tests indicate an excellent correlation between the rates at which drugs pass through ISCO’s lab-grown corneal tissue and rabbit corneal tissue. [International Stem Cell Corporation, Oceanside]
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Enhanced Stem Cells Promote Tissue Regeneration
Engineers have boosted stem cells’ ability to regenerate vascular tissue by equipping them with genes that produce extra growth factors (naturally occurring compounds that stimulate tissue growth). [Massachusetts Institute of Technology, Cambridge]
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Henry Ford Launches Gene Therapy Study for Parkinson’s Disease
The clinical trial will test whether gene transfer therapy is able to restore better mobility in Parkinson’s patients who have lost responsiveness to drug therapy. [Henry Ford West Bloomfield Hospital, West Bloomfield]
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Living Cell Technology Reports Successful First Implant Of DIABECELL(R) In New Zealand
The first of eight implants of encapsulated porcine cells that produce insulin was carried out under LCT’s clinical protocol for New Zealand. [Living Cell Technologies Limited, Auckland]
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ABSTRACTS, REVIEWS AND SPECIAL REPORTS
A Wound-induced Wnt Expression Program Controls Planarian Regeneration Polarity
The Smed-wntP-1 gene is required for regeneration polarity and is expressed at the posterior pole of intact animals in head-versus-tail regeneration polarity. [PNAS]
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Nucleation, Propagation and Cleavage of Target RNAs in Ago Silencing Complexes p754
Here, the crystal structures of ternary complexes of Thermus thermophilus Ago catalytic mutants, a family of proteins providing the slicer activity of the RNA-induced silencing complex, are reported and analyzed. [Nature]
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