|
SCIENCE NEWSTwo Genes Linked to Common Gynecological Disease
Scientists identified two new genetic variants that increase the risk of developing endometriosis, particularly moderate-severe forms. [Press release from the University of Oxford discussing online prepublication in Nature Genetics]New Mouse Model for Duchenne Muscular Dystrophy Implicates Stem Cells
Research and a new animal model of Duchenne muscular dystrophy point a finger squarely at the inability of human muscle stem cells to keep up with the ongoing damage caused by the disorder. [Press release from Stanford University School of Medicine discussing online prepublication in Cell] Protein Offers New Clue to Cause and Treatment for Kidney Disease
Researchers have pinpointed a protein that compromises the kidney's filtering ability, causing nephrotic syndrome, and demonstrated that a naturally occurring precursor of an acid in the body offers potential for treating some forms of the condition. [Press release from the University of Alabama at Birmingham discussing online prepublication in Nature Medicine] There’s a New “Officer” in the Infection Control Army
Scientists have identified a previously unrecognized step in the activation of infection-fighting white blood cells. The discovery also presents new opportunities to develop drugs to enhance the immune system, or to slow down hyperactive immune cells in cases of autoimmunity and cancer. [Press release from Johns Hopkins University School of Medicine discussing online prepublication in Molecular Cell] Study Reveals New Possibility of Reversing Damage Caused by MS
Damage caused by multiple sclerosis (MS) could be reversed by activating stem cells that can repair injury in the central nervous system, a study has shown. [Press release from the University of Cambridge discussing online prepublication in Nature Neuroscience] Study of How Genes Activate Yields Surprising Discovery
Scientists have made an unexpected finding about the method by which certain genes are activated. Contrary to what researchers have traditionally assumed, genes that work with other genes to build protein structures do not act in a coordinated way but instead are turned on randomly. [Press release from Albert Einstein College of Medicine of Yeshiva University discussing online prepublication in Nature Structural and Molecular Biology] Stem Cell Transplant Has Cured HIV Infection in 'Berlin Patient', Say Doctors
Doctors who carried out a stem cell transplant on an HIV-infected man with leukemia in 2007 say they now believe the man to have been cured of HIV infection as a result of the treatment, which introduced stem cells which happened to be resistant to HIV infection. [Press release from NAM Publications discussing online prepublication in Blood] Reproductive Scientists Create Mice from Two Fathers
Using stem cell technology, reproductive scientists at the M.D. Anderson Cancer Center have produced male and female mice from two fathers. [Press release from EurekAlert! discussing online prepublication in Biology of Reproduction] Experiments Suggest Possible New Approach to Stem Cell Therapy for Spinal Cord Injury
Initial experiments suggest a possible new approach to stem cell therapy for spinal cord injuries–using biocompatible “channels” made of chitosan to guide regeneration of new spinal cord tissue. [Press release from Wolters Kluwer Health discussing online prepublication in Neurosurgery] A 'Stitch in Time' Could Help Damaged Hearts
A research team has demonstrated the feasibility of a novel technology that a surgeon could use to deliver stem cells to targeted areas of the body to repair diseased or damaged tissue, including cardiac muscle damaged by a heart attack. The technique involves bundling biopolymer microthreads into biological sutures and seeding the sutures with stem cells. [Press release from Worcester Polytechnic Institute discussing online prepublication in the Journal of Biomedical Materials Research] Bioactive Peptides Found to Promote Wound Healing
Newly-created bioactive peptides, produced from collagenase treatment of extracellular matrix, promote wound healing through the growth of new blood vessels and epithelial tissue. [Press release from The Tufts Center for Innovations in Wound Healing Research discussing online prepublication in Wound Repair and Regeneration] “Grow Your Own Transplant” May be Possible for Men with Type 1 Diabetes
Men with type 1 diabetes may be able to grow their own insulin-producing cells from their testicular tissue, say researchers. [Press release from Georgetown University Medical Center discussing research presented at American Society of Cell Biology 50th Annual Meeting] First Fully Bioprinted Blood Vessels
Organovo, Inc. announced the release of data on the first fully bioprinted blood vessels. The blood vessels were created through the use of the NovoGen MMX Bioprinter, Organovo’s proprietary platform for the creation of 3D tissue constructs. [Press release from Organovo, Inc. discussing research presented at the Tissue Engineering and Regenerative Medicine International Society (TERMIS) North America Annual Conference and Exposition 2010] Can Transplanted Neuronal Progenitor Cells Develop into Functioning Neurons?
Investigators at the University of Florida have demonstrated that adult human neuronal progenitor cells generate functional neurons that integrate into host neuronal networks in the cerebral cortex. [Press release from Newswise discussing research presented at the 64th American Epilepsy Society Annual Meeting] MolMed Presents New Data for Its Cell Based Therapy TK at the Annual Meeting of the American Society of Hematology
MolMed S.p.A. presented an update on long-term follow up data of a completed Phase II trial (TK007) of its cell-based therapy TK for high-risk leukemia. [Press release from MolMed S.p.A. discussing research presented the 52nd Annual Meeting of the American Society of Hematology] Argos Therapeutics’ Arcelis™ HIV Immunotherapy Shows Feasibility to Generate Fully Functional Dendritic Cells from Viremic Patients
Argos Therapeutics announced that its Arcelis HIV immunotherapy, AGS-004, showed feasibility in in vitro models to generate fully functional dendritic cells from viremic patients. [Press release from Argos Therapeutics, Inc. discussing research presented at the HIV DART™ 2010 Conference] Researchers Developing Innovative Ways to Heal Severe Bone Fractures Through Combined Adult Stem Cell and Genetic Therapy
With the help of a $100,000 grant from the Orthopaedic Research and Education Foundation, researchers are developing innovative ways to overcome bone fracture-associated complications, such as bone grafts, synthetic bone replacement and multiple surgeries, by harnessing the body's own regenerative powers to restore lost bone by combining gene therapy and adult stem cell therapy. [University of Virginia Health System Press Release] Japan Team Say Stem Cells Helped Monkey Jump Again
Japanese researchers said they had used stem cells to restore partial mobility in a small monkey that had been paralyzed from the neck down by a spinal injury. [Associated Free Press] CURRENT PUBLICATIONS (Ranked by Impact Factor of the Journal) Directed Differentiation of Human Pluripotent Stem Cells Into Intestinal Tissue In Vitro
Researchers establish a robust and efficient process to direct the differentiation of human pluripotent stem cells into intestinal tissue in vitro using a temporal series of growth factor manipulations to mimic embryonic intestinal development. [Nature] Genome-Wide Association Study Identifies a Locus at 7p15.2 Associated with Endometriosis
Researchers conducted a genome-wide association study in 3,194 individuals with surgically confirmed endometriosis and 7,060 controls from Australia and the UK. Polygenic predictive modeling showed significantly increased genetic loading among 1,364 cases with moderate to severe endometriosis. [Nat Genet] Short Telomeres and Stem Cell Exhaustion Model Duchenne Muscular Dystrophy in mdx/mTR Mice
Researchers postulated that human Duchenne muscular dystrophy progression is a consequence of loss of functional muscle stem cells (MuSC), and the mild mouse mdx phenotype results from greater MuSC reserve fueled by longer telomeres. [Cell] Podocyte-Secreted Angiopoietin-Like-4 Mediates Proteinuria in Glucocorticoid-Sensitive Nephrotic Syndrome
Researchers show that the glomerular expression of angiopoietin-like-4, a secreted glycoprotein, is glucocorticoid sensitive and is highly upregulated in the serum and in podocytes in experimental models of minimal change disease and in the human disease. [Nat Med] The Dynamic Distribution of CARD11 at the Immunological Synapse Is Regulated by the Inhibitory Kinesin GAKIN
Investigators conducted an expression-cloning screen for modifiers of CARD11, a critical adaptor in antigen receptor signaling, and identified the kinesin-3 family member GAKIN as a CARD11 inhibitor. [Mol Cell] Retinoid X Receptor Gamma Signaling Accelerates CNS Remyelination
Results indicate that retinoid X receptor gamma is a positive regulator of endogenous oligodendrocyte precursor cell differentiation and remyelination and might be a pharmacological target for regenerative therapy in the CNS. [Nat Neurosci] Transcription of Functionally Related Constitutive Genes Is Not Coordinated
To directly measure the level of coordination in the expression of genes, researchers used highly sensitive fluorescence in situ hybridization to count individual mRNAs of functionally related and unrelated genes within single Saccharomyces cerevisiae cells. [Nat Struct Mol Biol] Evidence for the Cure of HIV Infection by CCR5(Delta)32/(Delta)32 Stem Cell Transplantation
Researchers demonstrate successful reconstitution of CD4+ T cells at the systemic level as well as in the gut mucosal immune system following CCR5(delta)32/(delta)32 stem cell transplantation, while the patient remains without any sign of HIV infection. [Blood] Generation of Viable Male and Female Mice from Two Fathers
Researchers used pluripotent stem cells derived from somatic cells to combine the haploid genomes from two males to produce viable sons and daughters. [Biol Reprod] Fibrin Microthreads Support Mesenchymal Stem Cell Growth While Maintaining Differentiation Potential
Researchers developed a method to produce discrete fibrin microthreads, which can be seeded with human mesenchymal stem cells and used as a suture to enhance the efficiency and localization of cell delivery. [J Biomed Mater Res A] Bioactive Peptides Derived from Vascular Endothelial Cell Extracellular Matrices Promote Microvascular Morphogenesis and Wound Healing In Vitro
Researchers postulated that matrix degradation by Clostridial collagenase creates bioactive fragments that can stimulate cellular responses to injury and angiogenesis. [Wound Repair Regen] 
|
|
POLICYStem Cell Funding Has Day in Court
Three federal appeals judges questioned lawyers on both sides of the lawsuit over whether federally funded research on human embryonic stem cells is illegal. [Court of Appeals, United States]
House Approves Flat 2011 Budget for Most Science Agencies
The three federal agencies that support the vast majority of academic research would receive no more money in 2011 than in 2010 under a spending bill that narrowly passed the House of Representatives. [House of Representatives, United States]
CIRM-MRC Human Somatic Cell Nuclear Transfer Workshop Report
Report of an Medical Research Council (MRC) and California Institute for Regenerative Medicine (CIRM) workshop to examine human somatic cell nuclear transfer and its role in stem cell research, summarizing the state of the global research effort in this area. [Medical Research Council, United Kingdom] 
|
|
BUSINESSCephalon and Mesoblast Enter Into Strategic Alliance to Develop and Commercialize Novel Therapeutic Products for Regenerative Medicine
Cephalon, Inc. and Mesoblast Limited announced they have entered into a strategic alliance to develop and commercialize novel adult Mesenchymal Precursor Stem Cell therapeutics for degenerative conditions of the cardiovascular and central nervous systems. The alliance also extends to products for augmenting hematopoietic stem cell transplantation in cancer patients. [Cephalon, Inc. Press Release] Sanofi-aventis Extends Tender Offer for All Outstanding Shares of Genzyme
Sanofi-aventis announced that it has extended its tender offer for all outstanding shares of common stock of Genzyme Corporation at $69.00 per share, net to the seller in cash, without interest and less any required withholding taxes. [Sanofi-aventis Press Release] Cytori Enters Strategic Equity Deal with Astellas Pharma; To Sell $10 Million in Equity at $7.00 per Share
Cytori Therapeutics and Astellas Pharma Inc. have entered into a strategic equity agreement to evaluate the potential of adipose derived stem and regenerative cells for the treatment of serious illnesses for which there is no fundamental treatment. [Cytori Therapeutics, Inc. Press Release]
Dicerna Pharmaceuticals and Kyowa Hakko Kirin Expand Dicer Substrate Technology Partnership Into Immunologic and Inflammatory Diseases
Dicerna Pharmaceuticals, Inc. and Kyowa Hakko Kirin Co., Ltd. announced the expansion of their ongoing research collaboration into the new therapeutic area of immunologic and inflammatory diseases. [Dicerna Pharmaceuticals, Inc. Press Release] Champions Biotechnology Announces Master Service Agreement with Teva Pharmaceutical Industries, Limited for the Evaluation of a Novel Oncology Compound
Champions Biotechnology, Inc. announced that a Master Service Agreement with Teva Pharmaceutical Industries has been commissioned for the testing of a novel anti-angiogenic compound in the Champions Tumorgraft™ platform. [Champions Biotechnology, Inc. Press Release] Johnson & Johnson Launches Recommended Public Offer to Acquire Crucell
Johnson & Johnson and Crucell N.V. announced that Johnson & Johnson, through its newly formed indirect wholly owned subsidiary, JJC Acquisition Company B.V., is making a recommended cash offer for all of the issued and outstanding ordinary shares in the capital of Crucell N.V., including all Ordinary Shares represented by American depositary shares (ADSs), each ADS representing one Ordinary Share at an offer price of EUR24.75 per Share. [Johnson & Johnson Press Release] Audax Medical Gains Rights to Brown Regenerative Nanotech
Medical device startup Audax Medical Inc. has gained exclusive rights from Brown University for Arxis, a biomaterial intended to help regenerate diseased bone and cartilage, the company reported. [Mass High Tech] University of Toronto-Hosted Project to Develop Regenerative Medicine Products Is Awarded $15 Million from the Federal Government
A University of Toronto-hosted project to develop products to treat devastating health conditions such as heart disease, diabetes, cancer and spinal cord injuries, The Centre for Commercialization of Regenerative Medicine, has been awarded $15 million by the federal government. [University of Toronto Press Release] $26 Million Boosts Stem Cell Research
A new $26.5-million stem cell research facility to be built at the University of Alberta will keep Edmonton at the forefront of regenerative medicine for patients with diabetes, burns, premature lungs and Parkinson's disease. [The Edmonton Journal] Aastrom Biosciences, Inc. Prices $22.5 Million Public Offering
Aastrom Biosciences, Inc. announced that it has priced a public offering of 10,000,000 units, with each unit consisting of one share of the Company's common stock and one warrant to purchase one share of common stock, at a purchase price of $2.25 per unit for an aggregate offering amount of $22.5 million. [Aastrom Biosciences, Inc. Press Release] ReNeuron Announces Fundraising
ReNeuron Group plc announced that it has raised £10 million, before expenses. [ReNeuron Group plc Press Release] CEL-SCI Corporation Receives Government Approval from Taiwan to Commence Phase III Clinical Trial of Multikine in Head and Neck Cancer
CEL-SCI Corporation announced it has received governmental approval from the Taiwanese Department of Health to begin enrollment of subjects for a Phase III clinical trial of Multikine® in Taiwan. [CEL-SCI Corporation Press Release] Biovex Commences OncoVEXGM-CSF Phase III Trial in Head and Neck Cancer
BioVex Inc. announced that a Phase III pivotal study with OncoVEXGM-CSF for the first line treatment of patients with locally advanced squamous cell carcinoma of the head and neck has commenced. [BioVex Inc. Press Release] Harvard Bioscience Files Two Major Patents in Field of Regenerative Medicine
Harvard Bioscience, Inc. has filed two major patents in the field of regenerative medicine, the first covering 61 claims for its stem cell therapy injectors and the second for 338 claims for bioreactors for organ growth. [Harvard Bioscience, Inc. Press Release] Regenerx Receives Mexican Patent for the Use of TB4 for Prevention and Treatment of Cardiac Damage
RegeneRx Biopharmaceuticals, Inc. announced that the Company received a patent from the Mexico Patent and Trademark Office for the use of thymosin beta 4 (TB4), its analogues, isoforms, and other derivatives, for preventing or healing the damage that occurs from a myocardial event. [RegeneRx Biopharmaceuticals, Inc. Press Release] SEBM European Best Poster Prize Awarded at Annual Conference of the German Society for Gene Therapy
Frauke Koenig, a PhD student in Professor Christoph Bräuchle'd group, in the Department of Physical Chemistry at the Ludwig Maximilians University Munich, was awarded this year's Society for Experimental Biology and Medicine (SEBM) European Prize for her work on live cell imaging of EGFR receptor targeting with short synthetic peptides. [EurekAlert!]
|
| | | |
| |
EVENTS (Listed by Date)
The 3rd Young Investigator Stem Cell Meeting
December 14, 2010
Tel Aviv, IsraelPartnering for Cures
December 14-15, 2010
New York, United States Pharmacology in Stem Cells Research and Regenerative Medicine
December 17, 2010
London, United Kingdom The 3rd Guangzhou International Conference on Stem Cell Biology and Regenerative Medicine
December 17-19, 2010
Guangzhou, China Functional Consequences of Structural Variation in the Genome
January 8-13, 2011
Steamboat Springs, United States 4th Annual OneMedForum
January 11-13, 2011
San Francisco, United States COGEM Symposium: GM Viruses as Medicine: Panacea or Pandora's Box?
January 20, 2011
Amsterdam, The Netherlands Extracellular Matrix and Cardiovascular Remodeling
January 23-28, 2011
Tahoe City, United States 5th Annual Stem Cells and Regenerative Medicine World Congress
January 24-25, 2011
San Diego, United States BIO Asia International Partnering Conference
January 24-25, 2011
Tokyo, Japan Phacilitate 7th Annual Cell & Gene Therapy Forum 2011
January 24-26, 2011
Washington, D.C., United States Phacilitate 9th Annual North American Vaccine Forum
January 24-26, 2011
Washington, D.C., United States IQPC’s 4th Biobanking Conference
January 24-26, 2011
Philadelphia, United States Keystone Symposia: Stem Cells in Development, Tissue Homeostasis and Disease
January 30-February 4, 2011
Santa Fe, United States 16th Proteomics Symposium
February 3-6, 2011
Lorne, Australia 36th Lorne Conference on Protein Structure and Function
February 6-10, 2011
Lorne, Australia CMC Workshop: Translating Science into Successful Regulatory Submissions
February 7-9, 2011
Washington, D.C., United States Stem Cell Research Forum of India 2nd Annual Meeting
February 8-11, 2011
Bangalore, India 23rd Lorne Cancer Conference
February 10-12, 2011
Lorne, Australia 32nd Lorne Genome Conference
February 13-15, 2011
Lorne, Australia BMT Tandem Meetings (ASBMT/CIBMTR)
February 17-21, 2011
Honolulu, Hawaii 1st Annual Clinical Meeting of the Cell Society
February 18-19, 2011
La Jolla, United States SMi Stem Cells 2011 – Innovation and Commercialisation
February 23-24, 2011
London, United Kingdom Molecular Medicine Tri-Conference: Stem Cells – Revolutionizing Regenerative Medicine and Personalized Therapy 2011
February 23-25, 2011
San Francisco, United States Molecular Medicine Tri-Conference: Inaugural Circulating Tumor Cells for Cancer Detection, Diagnosis, Prognosis and Treatment
February 23-25, 2011
San Francisco, United States American Association for Cancer Research (AACR) Targeting PI3K/mTOR Signaling in Cancer
February 24-27, 2011
San Francisco, United States Annual Meeting of the International Society for Cell & Gene Therapy of Cancer (ISCGT)
February 27-March 1, 2011
Doha, Qatar 9th Annual BioPartnering North America
February 27-March 1, 2011
Vancouver, Canada 18th Conference on Retroviruses and Opportunistic Infections (CROI 2011)
February 27-March 2, 2011
Boston, United States Cell Culture World Congress 2011 – Optimising Cell Culture Development for Biopharmaceutical, Bioprocessing and Manufacture
February 28-March 2, 2011
Munich, Germany 6th Annual Stem Cell Summit
March 1, 2011
New York, United States American Association for Cancer Research (AACR) Stem Cells, Development, and Cancer
March 3-6, 2011
Vancouver, Canada Keystone Symposia: Stem Cells, Cancer and Metastasis
March 6-11, 2011
Dillon, United States Cell Therapy Summit Europe (CTS Europe)
March 10-11, 2011
Maastricht, The Netherlands PITTCON Conference & Expo 2011
March 13-18, 2011
Atlanta, United States BIO-Europe Spring 2011
March 14-16, 2011
Milan, Italy The 6th International Conference on Oncolytic Viruses as Cancer Therapeutics
March 16-19, 2011
Las Vegas, United States 15th Annual Hilton Head Workshop – Regenerative Medicine, Innovations for Clinical Applications
March 16-19, 2011
Hilton Head Island, United States HIV Evolution, Genomics and Pathogenesis
March 20-25, 2011
Whistler, Canada StemCONN 11
March 22, 2011
Farmington, United States United Kingdom National Stem Cell Network 2011 Annual Scientific Conference
March 30-April 1, 2011
York, United Kingdom 10th Annual New England Science Symposium
April 1, 2011
Boston, United States American Association for Cancer Research (AACR) 102nd Annual Meeting 2011
April 2-6, 2011
Orlando, United States Clinical Gene Transfer: State of the Art Conference and e-Chips European Congress on Human iPS Cells
April 7-9, 2011
Paris, France 5th RNAi & miRNA World Congress
April 26-27, 2011
Boston, United States 3rd Epigenetics World Congress
April 26-27, 2011
Boston, United States Inaugural Next-Gen Sequencing Congress
April 26-27, 2011
Boston, United States GTCbio 2nd International Conference on Cancer Immunotherapy & Immunomonitoring
May 2-5, 2011
Budapest, Hungary Australasian Gene Therapy Society (AGTS) 7th Meeting
May 4-6, 2011
Melbourne, Australia BioPartnering India
May 4-6, 2011
Bangalore, India International Neural Transplantation and Repair 2011 (INTR11)
May 4-8, 2011
Clearwater Beach, United States World Stem Cells & Regenerative Medicine Congress 2011
May 9-11, 2011
London, United Kingdom 2nd European Biomarkers Summit
May 18-19, 2011
London, United Kingdom Inaugural Theranostics for Personalised Medicine
May 18-19, 2011
London, United Kingdom International Society for Cellular Therapy (ISCT) 17th Annual Meeting
May 18-21, 2011
Rotterdam, The Netherlands American Society of Gene and Cell Therapy (ASGCT) 14th Annual Meeting
May 18-22, 2011
Seattle, United States 13th Annual C21 BioVentures
May 24-26, 2011
Napa, United States Gordon Research Conference: Viruses & Cells
May 29-June 3, 2011
Lucca (Barga), Italy Tissue Engineering & Regenerative Medicine International Society (TERMIS) – Europe 2010 Annual Conference
June 7-10, 2011
Granada, Spain 9th Annual International Cord Blood Transplantation Symposium
June 9-11, 2011
San Francisco, United States Visit our events page to stay up to date with the latest events in the cell, gene and immunotherapy community.
JOB OPPORTUNITIES Lab Technologist – Cell Separation (STEMCELL Technologies) Lab Technologist – Human Embryonic and Induced Pluripotent Stem Cells (STEMCELL Technologies)
Lab Technologist – Tissue Culture (STEMCELL Technologies) Recruit Top Talent
Reach more than 11,000 potential candidates by posting your organization's career opportunities with Cell Therapy News at no cost.
Visit here to post your career opportunities.
|
| |
|
Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News
