4D Molecular Therapeutics and Roche Sign Collaboration Agreement for Gene Therapy Vector Discovery and Product Development 4D Molecular Therapeutics announced a collaboration and license agreement with Roche to discover and develop optimized next-generation AAV vectors for indications with high unmet medical need. [4D Molecular Therapeutics] Press Release Cell Therapy Catapult and Asymptote Collaborate to Revolutionize Delivery of Cell Therapies The Cell Therapy Catapult and Asymptote are combing forces to advance the development of a novel point-of-care thawing system for cell-based therapies. This device is intended to solve a global barrier to commercialization of cell therapies, by simplifying the delivery of these therapies to patients by addressing significant challenges of delivery at the point-of-care. [Cell Therapy Catapult] Press Release Spark Therapeutics and Clearside Biomedical Announce Exclusive Option to License Technology for Potentially Differentiated Delivery of Gene Therapy to the Eye Spark Therapeutics, Inc. and Clearside Biomedical, Inc. announced that they have entered into an option agreement under which Spark acquired exclusive rights to license Clearside’s microinjector technology to deliver gene therapies to the back of the eye. [Spark Therapeutics, Inc.] Press Release Bellicum Pharmaceuticals Licenses TCR Technology from Leiden University Medical Center Bellicum Pharmaceuticals, Inc. announced it has entered into a license agreement with Leiden University Medical Center for worldwide rights to develop, manufacture and commercialize high-affinity TCR (T cell receptor) product candidates targeting solid tumors expressing the preferentially-expressed antigen in melanoma, or PRAME. [Bellicum Pharmaceuticals, Inc.] Press Release NeoStem Announces First Patient Randomized in Pivotal Phase III Melanoma Immunotherapy Clinical Trial NeoStem, Inc. announced the randomization of the first patient in the Intus Phase III clinical trial investigating the efficacy of the company’s patient-specific targeted cancer immunotherapy candidate NBS20 in patients with stage III recurrent or stage IV metastatic melanoma. [NeoStem, Inc.] Press Release Cancer Treatment Centers of America at Western Regional Medical Center Launches Phase II of Innovative ‘PembroPlus’ Clinical Trial Cancer Treatment Centers of America® at Western Regional Medical Center has begun the Phase II portion of the first of six arms of this first-of-its-kind clinical trial, using a new immunotherapy treatment for patients with advanced small cell lung cancer, pancreatic cancer and connective-tissue cancers, including breast cancer. [Cancer Treatment Centers of America®] Press Release Amgen to Discuss Details of the Biologics License Application for Talimogene Laherparepvec for Patients with Metastatic Melanoma Amgen announced that the company discussed the data supporting the Biologics License Application for talimogene laherparepvec monotherapy for the treatment of patients with injectable regionally or distantly metastatic melanoma at a joint meeting of the U.S. Food and Drug Administration’s Cellular, Tissue and Gene Therapies Advisory Committee and Oncologic Drugs Advisory Committee. [Amgen Inc.] Press Release U.S. Food and Drug Administration Accepts Supplemental Biologics License Application for Opdivo (Nivolumab) in Patients with Previously Untreated Advanced Melanoma Bristol-Myers Squibb Company announced that the U.S. Food and Drug Administration has accepted for filing and review the supplemental Biologics License Application for Opdivo for the treatment of previously untreated patients with unresectable or metastatic melanoma. [Bristol-Myers Squibb Company] Press Release Advaxis Enhances Lm-LLO Cancer Immunotherapy Intellectual Property Portfolio with Two USPTO Patents Addressing ADXS-PSA and ADXS-HER2 Advaxis, Inc., a cancer immunotherapy company, announced that the United States Patent and Trademark Office (USPTO) has granted U.S. Patent No. 9,012,141 with composition of matter claims covering the Advaxis product candidate, ADXS-PSA, and U.S. Patent No. 9,017,660 with methods of use claims covering the Advaxis product candidate, ADXS-HER2. [Advaxis, Inc.] Press Release |