 | | Vol. 22.11 – 29 March, 2021 |
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| Reduction of protein/creatinin was observed in p53sh‐endothelial progenitor cell (EPC)‐transplanted mice more than null‐EPC or null‐mouse mesenchymal stromal cell transplanted mice.
[Journal of the American Heart Association] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Scientists developed CRISPR/Cas9 strategies to prevent aminoglycoside-induced deafness, a common type of acquired non-inherited sensorineural hearing loss, via disrupting the Htra2 gene in the inner ear which was involved in apoptosis but has not been investigated in cochlear hair cell protection.
[Genome Biology] |
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| The authors investigated the interaction between CD304 expression on myeloid-derived suppressor cells and galectin-1 from malignant plasma cells in the context of autologous stem cell transplantation for multiple myeloma.
[Cancer Immunology Research] |
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| Scientists analyzed bone marrow-MSCs from 66 patients after allo-hematopoietic stem cell transplantation, including 33 with active chronic graft-versus-host disease and 33 without chronic graft-versus-host disease.
[Cell Death & Disease] |
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| Researchers identified the insulin gene enhancer binding protein‐1 (ISL-1) protein as a potential modulator in bone marrow‐derived mesenchymal stem cell (BMSC)‐mediated revascularization of islet grafts.
[Stem Cells] |
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| Investigators found that only when human photoreceptor precursor cells were pre‐incubated with PKX‐001 prior to transplantation, did the cells integrate and mature into cone photoreceptors expressing S‐opsin or L/M opsin.
[Journal of Tissue Engineering and Regenerative Medicine] |
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| The Acute Leukemia Working Party/European Society for Blood and Marrow Transplantation registry was used to evaluate the outcomes of adult patients with acute lymphoblastic leukemia who underwent hematopoietic cell transplantation during 2011 through 2015 and compared them with the outcomes of those who underwent transplantation during 2016 through 2018.
[Cancer] |
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| Scientists investigated corneal reconstruction and tissue remodelling by transplantation of mesenchymal stem cells using temperature responsive membranes in chemically damaged rabbit cornea model.
[Graefe’s Archive for Clinical and Experimental Ophthalmology] |
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| The authors established a novel and robust monolayer differentiation method to produce functional neural progenitor cells (NPC) from hESC/iPSCs on Type I Collagen. The derived cells not only displayed the requisite markers, but also behaved similarly to classic NPCs both in vitro and in vivo.
[Science China LIfe Sciences] |
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| Advances are being made in cell-manufacturing approaches that have the potential to establish cell-therapies as credible therapeutic options. T-cell therapies face many challenges but hold great promise for improving clinical outcomes for patients with solid tumours.
[British Journal of Cancer] |
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| A number of immune regulatory cellular therapies, including regulatory T cells and mesenchymal stromal cells, have emerged as novel alternative therapies for the control of transplant alloresponses. Clinical studies have demonstrated their feasibility and safety, however developing our understanding of the impact of cellular therapeutics in vivo requires advanced immune monitoring strategies.
[Frontiers in Immunology] |
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| T-Cure Bioscience, Inc. announced that the company has entered into a clinical research agreement with Rutgers, The State University of New Jersey, to fund a Phase I clinical study testing a TCR-based product candidate for the treatment of tumors expressing Kita-Kyushu lung cancer antigen 1, such as gastric, cervical, lung, and triple negative breast cancers.
[T-Cure Bioscience, Inc. (Business Wire, Inc.)] |
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| Exacis Biotherapeutics Inc., announced several important steps in the pre-clinical development of its ExaNK™ engineered NK cell-therapy candidates.
[Exacis Biotherapeutics Inc. (PR Newswire LLC.)] |
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| April 13 – May 11, 2021
Virtual |
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| | University of Washington – Seattle, Washington, United States |
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| | NIH National Institute of Allergy and Infectious Diseases – Bethesda, Maryland, United States |
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| | The University of Iowa – Iowa City, Iowa, United States |
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| | Gladstone Institute – San Francisco, California, United States |
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| | Dana-Farber Cancer Institute – Boston, Massachusetts, United States |
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Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News
