 | | Vol. 22.20 – 7 June, 2021 |
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| Scientists showed that forced expression of C-X-C chemokine receptor type 6 in antigen-specific T cells enhanced the recognition and lysis of pancreatic cancer cells and the efficacy of adoptive cell therapy for pancreatic cancer.
[Nature Biomedical Engineering] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| The authors developed a one-step strategy using engineered lentiviral particles to introduce Cas9 ribonucleoproteins and a CAR transgene into primary human T cells without electroporation.
[Cell Reports] |
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| Adipose-derived mesenchymal stem cells were loaded with citric acid coated superparamagnetic iron oxide nanoparticles, systemically transplanted and magnetically recruited to the injured sciatic nerve.
[Acta Biomaterialia] |
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| Investigators tested the hypothesis that autologous bone-marrow mesenchymal stem cell (BM-MSC) administration in type 2 diabetes patient was safe and that the efficacy of the treatment was dependant on the quality of the autologous BM-MSC population and administration routes.
[Stem Cells Translational Medicine] |
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| The authors showed that conditional knockout of the demethylase Alkbh5 in bone marrow MSCs strengthened bone mass in mice.
[Cell Death & Disease] |
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| Researchers demonstrated that systemic transplantation of adult multipotent muscle-derived stem/progenitor cells- isolated from young mice-rejuvenates the knee articular cartilage of naturally aged mice.
[Aging and Disease] |
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| Investigators evaluated the in vitro and in vivo antitumor capability of adipose-derived mesenchymal stem cells as a new vehicle for Dearing strain of reovirus loading.
[Biochemical Pharmacology] |
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| Using RNA sequencing (RNA-seq) analysis, researchers showed that exon 3 and exons 7–10 of glypican 2 were expressed in cancer but was minimally expressed in normal tissues.
[Cell Reports Medicine] |
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| The authors discuss the various forms of cell therapy currently available, their utility in the management of immune-mediated inflammatory diseases and emerging evidence for efficacy in severe psoriasis unresponsive to biologic therapy.
[British Journal of Dermatology] |
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| The authors describe several recent advances in the field of anti-B-cell maturation antigen CAR T-cell therapy and multiple myeloma.
[Cancers] |
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| Sorrento Therapeutics, Inc. announced that the Company has entered into an additional collaborative agreement with NextGenNK Competence Center-associated research groups at the Department of Medicine, Huddinge, Karolinska Institutet  in Stockholm, Sweden, aimed at producing novel cell-based therapeutics using natural killer cells derived from induced pluripotent stem cells.
[Sorrento Therapeutics, Inc. (GlobeNewswire, Inc.)] |
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| MorphoSys AG and Constellation Pharmaceuticals, Inc. announced that they have entered into a definitive agreement whereby MorphoSys will acquire Constellation, a biopharmaceutical company developing novel therapeutics for myelofibrosis and hematological tumors.
[MorphoSys AG] |
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| Johnson & Johnson is walking away from a $1.6 billion blood cancer medicine deal with Belgium’s argenx for the CD70-targeting cusatuzumab.
[Johnson & Johnson (Questex, Inc.)] |
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| June 21 – 26, 2021
Virtual |
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| | Sana Biotechnology – Multiple Locations, United States |
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| | Shanghai Immune Therapy Institute – Shanghai, China |
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| | University of British Columbia – Vancouver, British Columbia, Canada |
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| | Cedars Sinai – Los Angeles, California, United States |
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| | Baylor College of Medicine – Houston, Texas, United States |
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Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News
