 | | Vol. 22.32 – 13 September, 2021 |
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| High-pressure homogenization is utilized to drive immunomodulator IL10-modified bacteria to extrude through the gap and self-assembled into bacterial biomimetic vesicles exposing IL10 on the surface with high efficiency.
[Advanced Materials] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| To investigate the feasibility, safety, and efficacy of theca stem cells (TSCs) transplantation in clinically relevant non-human primate models, researchers isolated TSCs from cynomolgus monkeys, and these cells were confirmed to expand continuously and show potential to differentiate into mature theca cells.
[Cell Discovery] |
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| Investigators used a porcine model to provide proof-of-concept evidence that a combination of amiodarone and ivabradine could effectively suppress engraftment arrhythmia.
[Stem Cell Reports] |
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| Scientists investigated post-transplant outcomes in 1722 myelodysplastic syndrome patients following Allogeneic hematopoietic-cell transplantation with fludarabine/treosulfan, reduced-intensity conditioning or myeloablative-conditioning.
[British Journal of Haematology] |
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| Investigators demonstrated that mouse hematopoietic stem cells could be efficiently expanded in polyvinyl alcohol-containing culture medium using only recombinant stem cell factor and thrombopoietin cytokines.
[Stem Cell Research] |
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| The authors showed dual regulatory functions of bone marrow-derived mesenchymal stem cells in attenuating hepatic fibrosis by promoting Ly6Chi/Ly6Clo subset conversion and Ly6Clo macrophage restoration through secreting antifibrogenic-cytokines and activating the apoptotic pathway.
[Cell Death Discovery] |
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| Researchers separated chicken bone marrow-derived mesenchymal stem cells (BM-MSCs); investigated whether BM-MSCs could improve lipopolysaccharide-induced lung and distal organ injury; and explored the underlying mechanisms.
[Scientific Reports] |
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| The authors evaluated the feasibility, safety, and efficacy of cell therapy based on mesenchymal stromal cells derived from adipose tissue intramuscular administration to patients with type 2 diabetes mellitus with critical limb ischemia and without possibility of revascularization.
[Trials] |
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| Three individuals with the traumatic spinal cord injury of the thoracic level were enrolled. They received the autologous olfactory ensheathing cell and MSC combination through the lumbar puncture.
[Spinal Cord] |
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| The pathophysiology of poor graft function can be conceptualized as dysfunction related to the number or productivity of the stem cell compartment, defects in bone marrow microenvironment components such as mesenchymal stromal cells and endothelial cells, or immunological suppression of post allogeneic stem cell transplant hematopoiesis.
[Blood Advances] |
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| Investigators review the molecular mechanisms of exosomes and internal microRNAs derived from MSCs in cardiac ischemic injury repair.
[Biomedicine & Pharmacotherapy] |
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| The authors provide an overview of recent scientific reports concerning novel strategies that promote MSC transplantation as an effective therapeutic approach, including physical approaches, chemical agents, traditional Chinese medicines and extracts, and genetic modification.
[Stem Cells International] |
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| Adaptimmune Therapeutics plc announced that it has entered into a strategic collaboration and license agreement with Genentech to develop and commercialize allogeneic cell therapies to treat multiple oncology indications. Adaptimmune will be responsible for developing clinical candidates using its iPSC derived allogeneic platform to produce T-cells.
[Adaptimmune Therapeutics plc] |
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| Bellicum Pharmaceuticals, Inc. and The University of Texas MD Anderson Cancer Center announced a global option and license agreement covering certain intellectual property and technology rights regarding Bellicum’s CaspaCIDe® safety switch and related technologies, and the use of rimiducid, an agent used to activate the safety switch.
[Bellicum Pharmaceuticals, Inc.] |
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| Sorrento Therapeutics, Inc. announced the start of enrollment in its Phase II efficacy study of human allogeneic adipose-derived mesenchymal stem cells for patients suffering from COVID-19-induced acute respiratory distress or acute respiratory distress syndrome in Brazil.
[Sorrento Therapeutics, Inc.] |
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| BioRestorative Therapies, Inc. announced that the Australian Patent Office has issued the company a patent related to its metabolic ThermoStem® Program.
[BioRestorative Therapies, Inc. (GlobeNewswire, Inc.)] |
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| September 22 – 24, 2021
Virtual |
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| | University of Louisville – Louisville, Kentucky, United States |
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| | University of Glasgow – Glasgow, Scotland, United Kingdom |
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| | Banner MD Anderson Cancer Center – Gilbert, Arizona, United States |
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| | St. Jude Children’s Research Hospital – Memphis, Tennessee, United States |
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| | University of Miami – Miami, Florida, United States |
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Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News
