| Vol. 23.07 – 7 March, 2022 |
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| The authors purified human biliary epithelial cells from human livers that were not used for liver transplantation. [Cell Stem Cell] |
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PUBLICATIONSRanked by the impact factor of the journal |
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| A rabies virus glycoprotein (RVG)-camouflaged gold yarnball that could boost the targeting efficiency at a brain tumor via dual hierarchy- and RVG-mediated spinal cord transportation, facilitating the decrease of tumor heterogeneity for T cell infiltration, was developed. [ACS Nano] |
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| Investigators treated three children suffering from severe, therapy-refractory GvHD with polyclonally expanded regulatory T cells generated from the original stem cell donor. [Molecular Therapy] |
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| Scientists described the generation of an array of monoclonal antibodies against cell surface markers that selectively label stem cell-derived islet cells. [Stem Cell Reports] |
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| The authors performed a phase I/IIa non-randomized, open-label study to evaluate safety and efficacy of a single, intravenous infusion of autologous, adipose-derived MSCs over a period of 52 weeks, in patients with active rheumatoid arthritis. [Stem Cell Research & Therapy] |
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| MSCs were comparable to N-acetylcysteine against acetaminophen (APAP)-induced liver failure by secreting hepatocyte growth factor with less regenerative retardation concerns, thus facilitating the application of MSCs in clinical therapy for APAP liver failure. [Stem Cell Research & Therapy] |
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| Abdominal adipose tissue-derived mesenchymal stem cell were harvested from patients without or with obesity during kidney donation or bariatric surgery, respectively. [International Journal of Obesity] |
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| Investigators developed targeted mesenchymal stem cell therapy for osteoarthritiscartilage using a cell-tissue matchmaking nanoconstruct. [Scientific Reports] |
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| Investigators provided an overview for the available management strategies for relapsed mantle cell lymphoma (MCL) and examines the role of CAR T cell in the current and future treatment of MCL. [Therapeutic Advances in Hematology] |
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| The field of heart regeneration has entered a renaissance period with remarkable progress in the understanding of endogenous heart regeneration, stem cell differentiation for exogenous cell therapy, and cell-delivery methods. [Developmental Cell] |
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| By harnessing the chemokine system and taking into consideration the chemokine expression profile in the tumor microenvironment, CAR-T cells may be homed into tumors to facilitate direct tumor cell cytolysis. [Cell Reports Medicine] |
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| The Yale Translational Research Imaging Center will be upgrading to a novel interventional cardiology ultrasound system, including 2D and 3D transthoracic, transesophageal, and high frequency vascular imaging probes. [Yale School of Medicine] |
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| Celyad Oncology SA announced it has taken the decision to voluntarily pause the CYAD-101-002 Phase Ib trial due to reports of two fatalities that presented with similar pulmonary findings. [Celyad Oncology] |
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| April 2 – April 3, 2022 Fukuoka, Japan, and Virtual |
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| Institute of Cancer Research – London, England, United Kingdom |
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| BioNTech – Gaithersburg, Maryland, United States |
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| Friedrich Miescher Institute for Biomedical Research – Basel, Switzerland |
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| Singapore-MIT Alliance for Research and Technology (SMART) Centre – Singapore, Singapore |
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| Babraham Institute – Babraham, England, United Kingdom |
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