 | | Vol. 23.30 – 20 June, 2022 |
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| Researchers showed that arming cytokine-induced memory-like natural killer cells with a neoepitope-specific CAR significantly enhanced their antitumor responses to nucleophosphmin-1 (NPM1)-mutated acute myeloid leukemia while avoiding off-target toxicity.
[Proceedings of the National Academy of Sciences of the United States of America] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| In a multi-site, cross-sectional study, clinical details and blood samples were collected from adults with clinically-diagnosed acute rejection of full thickness-corneal transplants (CT) and posterior lamellar-CT along with Stable CT recipients and adults with non-transplanted corneal disease.
[American Journal of Transplantation] |
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| Investigators constructed a nanoplatform termed dual-binding magnetic nanoparticles that comprised PEG-maleimide, hyaluronic acid and Fe3O4 for adoptive T cell-modification and adoptive cell therapy-sensitization.
[Journal of Nanobiotechnology] |
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| Mesenchymal stem cell were isolated from human placenta tissue, and DF-MSCs or Gluc-MSCs were generated by transduced with firefly luciferase/enhanced green fluorescence protein or Gaussia luciferase lactadherin fusion protein.
[Stem Cell Research & Therapy] |
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| Researchers conducted in vivo experiment on streptozotocin-induced diabetic rat model to test body weight, fasting blood glucose, serum ICAM-1 and VCAM-1 levels, histopathology and immunohistochemical staining of aorta segments.
[Stem Cell Research & Therapy] |
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| Scientists evaluated the anti-asthmatic effects of mesenchymal stem cells primed with Liproxstatin-1, a potent ferroptosis inhibitor.
[Scientific Reports] |
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| The effects of three different types of secretome derived from human mesenchymal stem cells were evaluated on cultured skin epithelial cells during 24, 48, 72 and 120 hours to determine the potential of this product to enhance cell proliferation and improve biofabrication strategies for tissue engineering.
[Scientific Reports] |
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| In the nine patients reported, neurological disease continued to progress after transplantation, manifesting as seizures, cerebellar disease and abnormalities of tone and reflexes.
[Orphanet Journal of Rare Diseases] |
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| Investigators summarize current knowledge on the cellular composition of the human bone marrow niche after hematopoietic cell transplantation.
[Bone Marrow Transplantation] |
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| The authors review the latest developments in cell therapy for corneal endothelial disease, highlighting the work of several groups that have reported successful functional outcomes of cell therapy in animal models.
[Current Opinion in Ophthalmology] |
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| A surgeon who just a decade ago was celebrated around the globe as a pioneer in stem cell transplants has been convicted of one count of “causing bodily harm,” a felony, in a Swedish court.
[ScienceInsider] |
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| It shouldn’t be a surprise that biotechs have already been in touch with Novartis to see whether they can jump onto the Swiss pharma’s T-Charge platform.
[Fierce Biotech] |
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| October 3 – 4, 2022
San Diego, California, United States |
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| | Columbia University – New York City, New York, United States |
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| | Washington University School of Medicine – St. Louis, Missouri, United States |
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| | New York Blood Center – New York, New York, United States |
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| | University of California, San Francisco – San Francisco, California, United States |
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| | University of Cambridge – Cambridge, England, United Kingdom |
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