 | | Vol. 23.21 – 27 June, 2022 |
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| Scientists designed a novel CAR-natural killer cells with a clinically significant tumoricidal effect on castration-resistant prostate cancer.
[Cancer Communications] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| Mesenchymal stem cells were isolated from human placenta tissue, and DF-MSCs or Gluc-MSCs were generated by transduced with firefly luciferase/enhanced green fluorescence protein or Gaussia luciferase lactadherin fusion protein.
[Stem Cell Research & Therapy] |
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| Scientists conducted in vivo experiment on streptozotocin-induced diabetic rat model to test body weight, fasting blood glucose, serum ICAM-1 and VCAM-1 levels, histopathology and immunohistochemical staining of aorta segments.
[Stem Cell Research & Therapy] |
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| The authors investigated the time to disappearance and appearance of isoagglutinins after ABO-incompatible allogeneic hematopoietic stem cell transplantation.
[Bone Marrow Transplantation] |
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| While intradermally injected vascular endothelial growth factor (VEGF)-loaded nanoparticles sufficed to induce a molecular rejuvenation signature in aged human skin on old mice, VEGF-A treatment improved key aging parameters also in isolated, organ-cultured aged human skin.
[Science Advances] |
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| Transplanted neonatal mesenchymal stem cells significantly increased the number of tissue reparative macrophages and regulatory T cells and decreased monocyte-derived inflammatory macrophages and neutrophils in the host myocardium.
[iScience] |
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| Investigators described the development of a CAR against the six-transmembrane epithelial antigen of prostate-1 (STEAP1), which is expressed in ∼90% of prostate cancers, and subgroups of other malignancies.
[Molecular Therapy-Oncolytics] |
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| Human umbilical cord mesenchymal stem cell-derived exosomes diminished NOTCH1 expression to accelerate M2 macrophage polarization via delivery of miR-146a-5p, thus alleviating systemic lupus erythematosus-associated diffuse alveolar hemorrhage in mice.
[Immunological Investigations] |
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| The authors showed that both cell-free and stem cell-seeded scaffolds exhibited superb healing compared with the empty defect controls, and new bone and connective tissues were formed in the healing site after 8 and 12 weeks, postoperatively.
[Journal of Orthopaedic Surgery and Research] |
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| Investigators review the beneficial effects of mesenchymal stem cell (MSC) transplantation in spinal cord injury clinical studies with a special focus on the MSC properties and limitations of MSC transplantation.
[Cell and Tissue Research] |
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| BioRestorative Therapies, Inc. announced it has reached an agreement with its second clinical site for its Phase II clinical trial targeting chronic lumbar disc disease.
[BioRestorative Therapies, Inc. (GlobeNewswire, Inc.)] |
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| TreeFrog Therapeutics announced the launch of The Stem Cell SpaceShot Grant, a $100,000 research funding in the field of stem cell biology and regenerative medicine.
[TreeFrog Therapeutics] |
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September 23 – 26, 2022
Prague, Czech Republic |
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| | The University of Arizona – Tucson, Arizona, United States |
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| | Columbia University – New York City, New York, United States |
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| | Washington University School of Medicine – St. Louis, Missouri, United States |
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| | New York Blood Center – New York, New York, United States |
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| | University of California, San Francisco – San Francisco, California, United States |
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Cancer Stem Cell News
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