 | | Vol. 24.10 – 27 March, 2023 |
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| In Phase I/II trials, scientists treated 67 subjects for CMV viremia or disease arising after allogeneic hematopoietic cell transplant with adoptive transfer of banked off-the-shelf, 3rd party, CMVpp65-sensitized T cells.
[Journal Of Clinical Investigation] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Investigators described an alternating magnetic field-manipulated tumor-homing bacteria developed by genetically modifying engineered Escherichia coli with Fe3O4@lipid nanocomposites.
[Nature Communications] |
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| Scientists described a Rhodiola rosea polysaccharides-based hydrophobic delivery vector and achieved an additional helpful antitumor effect by modulating tumor-associated macrophages.
[International Journal Of Biological Macromolecules] |
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| A constructed aligned porous hydrogel scaffold carrying cells based on chitosan and oxidized chondroitin sulfate treated with a freeze-casting technique was fabricated, which aimed to induce the arrangement of periodontal tissue regeneration.
[ACS Biomaterials Science & Engineering] |
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| Researchers established a workflow using induced pluripotent stem cell-derived fibroblasts and skeletal myocytes for urethral tissue regeneration, allowing scalable derivation, culture, and in vivo tracing of patient-specific fibroblasts and myocytes.
[Scientific Reports] |
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| A combined therapeutic strategy was tested by using GD2 CAR T together with Nivolumab, an anti-PD-1 monoclonal antibody. Animal studies suggested that GD2 CAR T effectively infiltrated into tumor tissue and significantly hampered tumor progression.
[Translational Oncology] |
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| To improve immune checkpoint blockade, fexofenadine, an antihistamine, was encapsulated into aptamer-modified nanostructure to make a drug-loaded nanoparticle.
[Journal Of Cancer Research And Clinical Oncology] |
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| Scientists assessed the application of novel 3D printed scaffolds and induced pluripotent stem cell-derived mesenchymal stem cells overexpressing the transcription factor Scleraxis as a new strategy for tendon defect repair.
[Journal Of Orthopaedic Research] |
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| Investigators successfully fabricated polycaprolactone salt-leached scaffolds with two levels of a biomimetic calcium phosphate coating to examine their effects on mesenchymal stem cell osteogenesis.
[Cells Tissues Organs] |
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| The authors describe the potential for cell and gene therapy in treating kidney disease, focusing on recent genetic studies, key advances, and emerging technologies, describing several crucial considerations for renal genetic and cell therapies.
[Nature Reviews Nephrology] |
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| Investigators review stem cell-based immunotherapy approaches, stem cell sources, gene engineering and manufacturing strategies, therapeutic platforms, and clinical trials, as well as challenges and future directions for the field.
[Cell Stem Cell] |
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| Aurion Biotech announced it has received regulatory approval from Japan’s Pharmaceuticals and Medical Devices Agency (PMDA), for its novel cell therapy, VyznovaTM for the treatment of bullous keratopathy of the cornea.
[Aurion Biotech] |
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| April 17 – 19, 2023
Lund, Sweden |
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| | Novartis – East Hanover, New Jersey, United States |
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| | Dana-Farber Cancer Institute and Harvard Medical School – Boston, Massachusetts, United States |
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| | Umeå University – Umeå, Sweden |
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| | University of Florida – Gainesville, Florida, United States |
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| | Delft University of Technology – Delft, Netherlands |
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Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News
