 | | Vol. 24.11 – 3 April, 2023 |
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| Scientists investigated the paracrine function of the secretome from hypoxia preconditioned mesenchymal stem cells in articular cartilage injury, in comparison to normoxia secretome.
[Bioactive Materials] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Investigators fabricated biofunctional cell-laden structures including methacrylated gelatin, collagen, and decellularized extracellular matrix. In vivo regenerative potential was observed in volumetric muscle defects in a mouse model.
[NPJ Regenerative Medicine] |
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| RNA molecules commercially available for immunomodulatory applications (imRNA) were used to prepare biomaterials for bone regeneration. It was shown that incorporating imRNA-ACP into collagen scaffolds resulted in rapid new bone formation in cranial defects of mice.
[Acta Biomaterialia] |
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| Scientists found decreased CD30 expression in refractory/relapsed classic Hodgkin lymphoma in patients who underwent CAR T cell therapy in their institution between 2018 and 2022.
[Histopathology] |
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| Researchers hypothesized that localized T cell delivery in an in situ gelling chitosan hydrogel will allow similar treatment efficacy despite delivering fewer cells than systemic intravenous delivery.
[Biomaterials Science] |
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| Investigators presented a first-in-human study assessing the safety and efficacy of novel DEC cell therapy created by fusion of patient myoblasts with myoblasts of normal donor origin.
[Stem Cell Reviews And Reports] |
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| Researchers retrospectively reviewed 99 patients with refractory or relapsed multiple myeloma treated with B cell maturation antigen (BCMA)-targeted CAR-T cell therapy, of which 7 patients had chronic HBV infection, 43 with resolved HBV infection, and the remaining 49 HBV-uninfected.
[Bone Marrow Transplantation] |
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| To overcome the limitations of lymphedema treatment, human adipose-derived stem cells were injected into decellularized lymph nodes to produce a recellularized lymph node-scaffold, and the effect of lymphangiogenesis was investigated in lymphedema animal models.
[Scientific Reports] |
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| Researchers investigated the changes in cardiac and inflammatory biomarkers in CAR T therapy to determine the role of pro-inflammatory cytokines.
[Cardio-Oncology] |
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| The authors address pore-engineered nanoarchitectonics with application targets for cancer therapy by combining basic descriptions and exemplifying therapy applications.
[Npg Asia Materials] |
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| US FDA official Peter Marks said he hopes to align global regulations to boost commercialization for gene and cell therapies to get more treatments launched for patients with rare diseases.
[Reuters] |
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| April 11 – 12, 2023
New York, New York, United States |
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| | Medical University of South Carolina – Charleston, South Carolina, United States |
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| | Novartis – East Hanover, New Jersey, United States |
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| | Dana-Farber Cancer Institute and Harvard Medical School – Boston, Massachusetts, United States |
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| | Umeå University – Umeå, Sweden |
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| | University of Florida – Gainesville, Florida, United States |
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Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
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