 | | Vol. 24.20 – 12 June, 2023 |
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| Researchers reported a bioinspired material, engineered fusogen and targeting moiety co-functionalized cell-derived nanovesicle (CNV) called eFT-CNV, as a drug vehicle.
[Nature Communications] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Investigators used the heterologous expression of gene clusters to generate genetically engineered bacteria that could produce numerous sub-micron gas vesicles in the bacterial cytoplasm.
[Nature Communications] |
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| Scientists improved the function of CAR-T cells against cholangiocarcinoma through knock-down immune checkpoints and immunosuppressive molecular receptors.
[Cancer Communications] |
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| Inspired by the development of synergistic therapeutic strategies, researchers proposed a novel nanovaccine-based platform to achieve chemotherapy, ferroptosis therapy, and immunotherapy simultaneously.
[Nanoscale Horizons] |
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| Building on development of self-organizing culture to generate pituitary-hypothalamic organoids (PHOs) using human pluripotent stem cells (hPSCs), the authors established techniques to generate PHOs using feeder-free hPSCs and to purify pituitary cells.
[Stem Cell Reports] |
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| Researchers established single cell-derived neural stem/progenitor cells clones (scNS/PCs) from human induced pluripotent stem cells (hiPSC)-NS/PCs that generated undesired grafts.
[Communications Biology] |
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| The authors investigated the properties of lipid nanoparticles-mRNA systems prepared with high levels of “helper” lipids such as distearoyl phosphatidylcholine or egg sphingomyelin.
[Molecular Therapy-Methods & Clinical Development] |
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| Researchers fabricated decellularized periosteum (DP) and investigated its immunomodulatory properties in guided bone regeneration. DP was successfully fabricated from periosteum from the mini-pig cranium.
[Biotechnology Journal] |
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| Scientists showed that even with the background of prolonged immunosuppression for solid organ transplant, it was possible to generate autologous CAR-T products capable of expansion and persistence in vivo, without evidence of excess T cell exhaustion.
[Human Vaccines & Immunotherapeutics] |
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| Investigators describe recent advances in engineering solutions for the development of localized immunomodulation techniques focusing on cellular and organoid transplantation.
[Trends In Molecular Medicine] |
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| Bristol Myers Squibb announced that the US FDA has approved commercial production at the company’s newest cell therapy manufacturing facility in Devens, Massachusetts.
[Bristol Myers Squibb] |
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| June 28 – 30, 2023
Kyoto, Japan |
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| | University College London – London, England, United Kingdom |
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| | VIB-UGent Center for Medical Biotechnology – Ghent, Belgium |
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| | Massachusetts Institute of Technology – Cambridge, Massachusetts, United States |
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| | Centre for Oncology and Immunology – Hong Kong, Hong Kong |
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| | Weill Cornell Medical College – New York, New York, United States |
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