Cell Therapy News Volume 9.05 | Feb 11 2008

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    Cell Therapy News 9.05, February 11, 2008
         In this issue: Science | Policy | Business | NIH | CBER | Regulatory
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    Top Stories

    Scientists Develop Skin from Hair Cells: In a breakthrough for patients with serious burns and chronic wounds, German researchers have developed a method to artificially grow skin cells in a lab that are derived from a patient’s own stem cells found within hair roots.
    Article

    Stem Cell Activity Follows Circadian Rhythyms: The effectiveness of stem cell therapies may rely not only on the nature of the cells involved, but the time of their application.
    Article

    Science

    Cancer Biomarkers Development and Clinical Use
    June 16, 2008 |  New York, New York

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    Embryos with Three Parents Created in Lab
    British scientists have created human embryos with three parents in a development they hope could lead to effective treatments for a range of serious hereditary diseases within five years.
    Article

    Stem Cells May Help Trial Drugs
    Drugs could be screened for potential harmful side-effects before they are trialled in patients using pioneering stem cell research.
    Article

    Gene Therapy Shows Promise for HIV
    For the first time, researchers have slowed and possibly stopped the AIDS virus from reproducing in patients by using a gene therapy that tricks it into self-destructing.
    Article

    New Direction for Gene Therapy
    Researchers have identified a new strategy for circumventing the safety problems that have plagued gene therapy according to a study published online in Cell.
    Article

    Tattoos May Help Deliver Vaccine
    Scientists in Germany say that tattoos could be the ideal way of delivering vaccines into the body.
    Article

    See-through Fish is Created to Give a Clearer Idea of How Cancer Spreads
    A transparent zebrafish has been engineered to allow scientists to watch how cancers develop and behave inside the body in real time.
    Article

    Molecular Therapy Succeeds in Preventing Craniofacial Birth Defect in Mice
    A new gene-based technique has successfully prevented a rare craniofacial birth defect in mice and holds promise to help children with the same disorder.
    Article

    Alnylam Reports Pre-clinical Progress with RNAi Therapeutics in Neurological Disease
    The new study, performed in collaboration with scientists Xandra Breakefield, Ph.D., Bakhos Tannous, Ph.D., and Jeffrey Hewett, Ph.D., from Massachusetts General Hospital, describes the silencing of a key gene implicated in early onset torsion dystonia, known as mutant torsinA.
    Article

    New Victories for Adult Stem Cell Research Scientists Make Headway in Treating Damaged Hearts with Muscle, Fat and Bone Marrow Cells
    Two studies show encouraging promise in using adult muscle stem cells derived from a patients own thigh tissue to treat advanced heart failure.
    Article

    Cord Blood Registry Reports a Significant Increase in Number of Children Needing Access to Their Own Cord Blood Stem Cells for Treatment
    Cord Blood Registry has announced that for the second year in a row, a record number of cord blood stem cell collections stored at CBR have been needed for medical use by the individual child from whom they were collected.
    Article

    ACOG Revises Opinion On Cord Blood Banking
    Physicians should give balanced information to their pregnant patients who are considering cord blood banking, presenting both the advantages and disadvantages of public vs. private cord blood banks, according to The American College of Obstetricians and Gynecologists in a revised Committee Opinion published today in the February issue of Obstetrics & Gynecology.
    Article

    ABSTRACTS, REVIEWS AND SPECIAL REPORTS

    Human Embryonic Stem Cell Lines Generated without Embryo Destruction
    The researchers report the derivation of five hESC lines without embryo destruction, including one without hESC coculture.
    Article

    Transplants of Encapsulated Rat Choroid Plexus Cells Exert Neuroprotection in a Rodent Model of Huntington’s Disease
    These data demonstrate that transplanted choroid plexus cells can be used to protect striatal neurons from excitotoxic damage and that the pattern of neuroprotection varies across specific neuronal populations.
    Article

    JOB OPPORTUNITIES

    Cell Therapy Business Development Leader
    Portland, OR (Invitrogen)
    Link

    Scientist
    Irvine, CA (Global Biopharmaceutical Company)
    Link

    Biomedical Equipment Technician
    Los Angeles, CA (Cedars-Sinai Medical Center)
    Link

    Quality Manager
    Singapore (Singapore Cord Blood Bank)
    Link

    Policy

    Bush Staff, Tech Titans Split Over Patent Bill
    The Bush administration has said that it opposes a key provision of a patent reform bill that has passed the House of Representatives and is awaiting a floor vote in the Senate, taking sides in an intellectual war over how best to promote innovation.
    Article

    Stem Cell Institute Wants to Make Loans
    California’s taxpayer-funded stem cell institute wants to do something a lot of banks won’t: make loans to biotechnology companies with no cash flow, very little collateral and a high risk of failure.
    Article

    California Stem Cell Institute Gets 50 Applications for Cell Line Funding
    CIRM will give as many as 16 awards of up to $25 million for development of new lines of pluripotent human stem cells for research and clinical use to study, diagnose and treat serious injury and disease.
    Article

    Stem Cells Nudge Closer to Ballot Spot
    Campaigns to lift Michigan’s restrictions on embryonic stem-cell research and to scrap much of the state tax system got the go-ahead Monday to begin circulating petitions in an effort to put the issues before voters in November.
    Article

    United Kingdom Ministers Back Down on Stem Cell Cloning Ban
    The Government is to back down from introducing strict curbs on stem-cell experiments after a plea by scientists.
    Article

    Stott-Despoja Ignites New Stem Cell Row
    Australian senator Natasha Stott-Despoja has begun lobbying state MPs to support stem cell research legislation, sparking a political row with opponents of the move.
    Article

    Business

    WaferGen Signs Exclusive Distribution Agreements for SmartSlide(TM) Micro-Incubation System in Australia, Singapore and the Benelux
    WaferGen Biosystems, Inc. has announced the signing of exclusive distribution agreements for the company’s SmartSlide Micro-Incubation System with INBIO in Australia, ScienceWerke Pte. Ltd. in Singapore and Westburg B.V. in the Benelux countries.
    Article

    South Korean Stem Cell Firm Enters Into an Agreement with Tiantan Puhua Hospital in China
    RNL Bio entered into an agreement with Tiantan Puhua Hospital for stem cell treatments for complications including spinal cord injury, hair loss and osteoarthritis.
    Article

    AssureImmune Launches Premier Services in South Florida
    AssureImmune LLC, a company specializing in collecting and preserving adult stem cells, today announced its launch of premier banking services in South Florida.
    Article

    GeneMole “Personal” Automated DNA Extraction System Launched in Europe
    Mole Genetics has launched the new GeneMole(R) automated DNA extraction system in Europe following successful trials in the Nordic region.
    Article

    Geron’s Second U.S. Patent for Production of Pancreatic Islets from Human Embryonic Stem Cells Strengthens Company’s Intellectual Property Position
    Geron Corporation has announced that it has received U.S. Patent 7,326,572 with claims covering a widely used method for producing endoderm cells from human embryonic stem cells.
    Article

    Cohen, Milstein, Hausfeld & Toll, P.L.L.C. Announces Class Action Lawsuit on Behalf of Investors of CellCyte Genetics Corporation
    The law firm of Cohen, Milstein, Hausfeld & Toll, P.L.L.C. has announced that it has filed a class action complaint in the United States District Court for the Western District of Washington on behalf of purchasers of CellCyte Genetics Corporation common stock from April 6, 2007 through January 9, 2008, inclusive.
    Article

    Juvenile Diabetes Foundation to Fund Plureon Research
    The Juvenile Diabetes Research Foundation will provide $500,000 over two year to fund research at Plureon Corp. into new treatments for type 1 diabetes.
    Article

    NIH

    NIDDK Welcomes Four New Members to Advisory Council
    Health and Human Services Secretary Mike Leavitt appointed four new members to the Advisory Council of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), the institute announced today. NIDDK is part of the National Institutes of Health (NIH) of the U.S. Department of Health and Human Services.
    Article

    Notice of Change in Receipt Date and NIBIB Contact Person on TPA-06-504, Enabling Technologies for Tissue Engineering and Regenerative Medicine (NOT-EB-08-001)
    Link

    Rare Diseases Clinical Research Consortia (RDCRC) for the Rare Diseases Clinical Research Network (U54) (RFA-OD-08-001)
    Link

    CBER

    Licensed Products and Establishments List – Update
    Link

    Approved Biological NDA and ANDA Applications – Update
    Link

    Clinical Hold/Refusal to File Meetings – 2008 Schedule
    Link

    Eligibility Determination for Donors of Human Cells, Tissues, and Cellular and Tissue-Based Products (HCT/Ps)
    Link

    HCT/P Compliance Update
    Link

    Regulatory

    FOOD AND DRUG ADMINISTRATION (United States)

    FDA Budget Seeks Biotech Generics and User Fees
    New fees for the Food and Drug Administration to speed review of generic pharmaceuticals and new authority to approve copycat versions of some biotech drugs were proposed in President George W. Bush’s budget.
    Article

    ISCT

    14th ISCT Annual Meeting

    May 17-20, 2008
    Downtown Miami, Florida

    Full details at: http://www.celltherapysociety.org


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