Cord Blood News 11.33 August 29, 2019 | |
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TOP STORYThe authors examined the association of prenatal bisphenol A exposure with genome-wide DNA methylation changes in cord blood in 277 mother-child pairs in the Hokkaido Study on Environment and Children’s Health, using the Illumina HumanMethylation 450 BeadChip. [Sci Rep] Full Article | |
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PUBLICATIONS(Ranked by impact factor of the journal)Investigators prospectively compared immune recovery patterns of lymphocyte subsets among four groups of adult patients with hematological disease who received hematopoietic cell transplantation from either HLA‐matched related or HLA‐matched unrelated donors, cord blood transplantation, or reduced‐dose post‐transplantation high‐dose cyclophosphamide. [Transpl Int] Abstract The membranes exhibited excellent biocompatibility upon estimation of their cytotoxicity on Wharton’s jelly mesenchymal stromal cells (WJ-SCs), while they presented higher osteogenic potential in comparison with neat poly(ε-caprolactone) after WJ-SCs induced differentiation towards bone cells, which was enhanced by a possible synergistic effect of Sr and ibandronate. [Molecules] Full Article Researchers investigated the therapeutic effect of hepatocyte growth factor-transfected human umbilical cord blood-derived MSCs on dimethylnitrosamine-induced liver fibrosis in rats. [Growth Factors] Abstract This case report presents the results of distal femoral osteotomy and human umbilical cord blood-derived MSC implantation for treating two patients with valgus deformity who had lateral compartment osteoarthritis. [Knee] Abstract Mesenchymal Stromal Cells Lower Platelet Activation and Assist in Platelet Formation In Vitro Scientists developed a potentially novel culture system for supporting platelet formation in vitro using a unique population of CD51+PDGFRα+ perivascular cells, derived from human umbilical cord tissue, which displayed numerous MSC properties. [JCI Insight] Full Article Subscribe to one of our other 19 science newsletters such as Hematopoiesis News & Cell Therapy News. | |
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REVIEWSMesenchymal Stem Cells in Allergic Diseases: Current Status The authors focus on the discoveries and biological mechanisms of MSCs as a therapeutic tool in allergic diseases. They discuss the challenges of conducting MSC studies as well as future directions. [Allergol Int] Abstract Visit our reviews page to see a complete list of reviews in the cord blood research field. | |
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INDUSTRY NEWSBaylor Awarded CPRIT Grants to Support Cancer Research Baylor College of Medicine has been awarded more than $17.4 million by the Cancer Prevention & Research Institute of Texas (CPRIT) to support new cancer research and programs, core facilities and recruitment of new faculty. More than 70 grants were awarded to institutions across Texas, totaling close to $136 million to advance the fight against cancer, including nine grants to Baylor College of Medicine. [Baylor College of Medicine] Press Release IU School of Medicine Researcher Hal Broxmeyer Awarded IU President’s Medal “Dr. Broxmeyer’s work in the area of human umbilical cord blood as a source of transplantable hematopoietic stem cells truly has been pioneering,” Indiana University (IU) President Michael A. McRobbie said. “His research has brought much closer the possibilities of a cure in some forms of cancer and blood diseases in children and adults.” [Indiana University School of Medicine] Press Release | |
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POLICY NEWSYounger Scientists Need Better Support Letters from research funders to university leaders rarely raise eyebrows. But a letter sent this month by the heads of the United Kingdom’s three largest medical-research funders did just that. [Nature News] Editorial FDA Warns Testing Companies: Don’t Tell Patients How Their DNA Influences Response to Specific Drugs Amid a boom in genetic testing that aims to predict a person’s response to medication, the FDA has been quietly pressuring a handful of companies to stop reporting results to patients about how their genes may interact with specific drugs. [STAT News] Editorial Australia Plans to Tackle Foreign Influence at Nation’s Universities In response to growing concerns in Australia about foreign influence at universities, cyberspying, and a perceived erosion of freedom of speech on campuses, the country’s education minister announced that a new task force will develop “best-practice guidelines for dealing with foreign interference.” [ScienceInsider] Editorial
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EVENTSNEW Stromal Cells in Immunity and Disease Visit our events page to see a complete list of events in the community.
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JOB OPPORTUNITIESNEW Postdoctoral Researcher – Cell Cycles in Stem Cells (University of California, Santa Cruz) Scientific Communications Coordinator (STEMCELL Technologies Inc.) Postdoctoral Studies – Normal and Aberrant Hematopoiesis (Karolinska Institutet) Postdoctoral Scholarship – Human Erythropoiesis (Lund University) Postdoctoral Scholarship – Computational Genomics and Bioinformatics (Lund University) Postdoctoral Scholar – Gene and Cell Therapy (Stanford University) Associate Professor – Pediatrics (Pennsylvania State University) Early Stage Researchers – Hematopoiesis (Multiple Locations) PhD Positions – Age-Related Changes in Hematopoiesis (University of Milano-Bicocca) Recruit Top Talent: Reach potential candidates by posting your organization’s career opportunities on the Connexon Creative Job Board at no cost.
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