| Vol. 12.25 – 9 July, 2020 |
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| Physician-investigators at Johns Hopkins University Hospital report on the promising data of treatment of COVID-19 induced acute respiratory distress syndrome with allogeneic, cord blood derived T-regulatory cell therapy. [Annals of Internal Medicine] |
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PUBLICATIONSRanked by the impact factor of the journal |
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| Of ten compounds tested, only the Bromodomain and Extra-terminal Motif inhibitor CPI203 enhanced the expansion of human cord blood hematopoietic stem cells without losing cell viability in vitro. [Blood] |
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| Investigators observed increased migration and reduced proliferation and differentiation when keratinocytes were co-cultured in media conditioned by human amniotic epithelial cells and human amniotic mesenchymal stem cells. [Aging-Us] |
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| Researchers showed that cellular senescence occurred in the Stem Regenin 1‐expanded hUCB CD34+ cells in which p38 mitogen‐activated protein kinase α (p38α) and mammalian target of rapamycin complex 1 (mTORC1) were successively activated. [Stem Cells Translational Medicine] |
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| Scientists proposed a new dual‐enzymatically cross‐linked and injectable gelatin hydrogel for regulating survival, proliferation and differentiation of human umbilical cord mesenchymal stem cells in three‐dimensional matrix. [Journal of Tissue Engineering and Regenerative Medicine] |
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| Investigators reprogrammed the stem cells from the Wharton’s jelly of umbilical cords of gestational diabetes mellitus (GDM) and non-GDM mothers into induced pluripotent stem cells and then differentiated the iPSCs into insulin-producing cells to provide pancreatic tissues that represent the fetus of GDM and normal mothers. [Stem Cell Research] |
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| Researchers found that human umbilical MSC-exosomes accelerated skin wound healing and angiogenesis, inducing a higher wound-closure rate and increased expression of CD31 in vivo. [Stem Cell Reviews and Reports] |
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| Wharton’s jelly mesenchymal stem cells were treated with a 0.4-T static magnetic field. The cell viability was tested using the MTT assay. [International Journal of Radiation Biology] |
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| Umbilical cord blood is readily available, has low immunogenicity, and does not require as strict of human leukocyte antigen matching compared to other graft sources. [Stem Cells Translational Medicine] |
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| A new US immigration policy, which threatens to revoke visas for certain international students if they are not taking in-person classes, is stirring panic and confusion and causing some universities to push back with lawsuits. [Science] |
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| The new director of the National Science Foundation (NSF), Sethuraman “Panch” Panchanathan, is familiar with the dark clouds over the agency. His boss, President Donald Trump, keeps proposing big cuts to NSF’s budget. Two recent executive orders on immigration make it harder for foreign scientists—who make up a sizeable share of the U.S. research enterprise—to enter the country. [Science] |
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| October 20 – October 21 Virtual |
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| University of Pennsylvania Health System – Philadelphia, Pennsylvania, United States |
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| Northwestern University – Chicago, Illinois, United States |
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| Columbia University – New York, New York, United States |
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| Duke University – Durham, North Carolina, United States |
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| University of Colorado – Denver, Colorado, United States |
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