| Vol. 12.28 – 30 July, 2020 |
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| Investigators mapped expression quantitative trait loci in resting myeloid cells and CD4+ T cells from cord blood samples, as well as in response to lipopolysaccharide or phytohemagglutinin stimulation, respectively. [Nature Communications] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| Researchers report serial changes in six circulating, cross-species/bridging biomarkers in a clinically relevant porcine model of neonatal hypoxic ischemic encephalopathy with functional analysis. [Molecular Neurobiology] |
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| Umbilical cord (UC)-derived MSCs were isolated from 10 UC tissue samples by both explantation and enzymatic digestion methods to allow for comparison of cells from the same donor. [Cytotherapy] |
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| Investigators evaluated the effects of human bone marrow (hBM)-conditioned medium derived from different stages of hBM MSC culture on the osteogenic capacity of perivascular tissue of the human umbilical cord. [Tissue Engineering] |
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| The authors conducted a Phase I/II clinical trial aiming to evaluate the safety and efficacy of intravenous administration of umbilical cord MSCs in advanced retinitis pigmentosa patients. [Stem Cells and Development] |
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| Scientists investigated the effect of recombinant human bone morphogenetic protein-7 and/or osteogenic media on bone regeneration of human umbilical cord-MSCs seeded on nano-hydroxyapatite/collagen/poly (L-lactide) in a rabbit model. [Stem Cells and Development] |
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| The authors report a patient with adult T‐cell leukemia/lymphoma, who developed paroxysmal nocturnal hemoglobinuria seven years after umbilical cord blood transplantation. [European Journal of Haematology] |
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| The authors used a post-test control group design. MSCs were obtained from human umbilical cord blood and characterized according to their surface antigen expression and multilineage differentiation capacities. [Journal of the Formosan Medical Association] |
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| Scientists investigated immunomodulatory potential of human Wharton’s jelly mesenchymal stem cells derived extracellular vesicles on inflammasome activity one week after spinal cord injury in rats. [Neuroscience Research] |
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| Ex vivo hematopoietic stem cell derivation from renewable sources such as induced pluripotent stem cells offers an experimental tool for studying developmental hematopoiesis, disease modeling, and drug discovery, and yields tremendous therapeutic potential for malignant and nonmalignant hematological disorders. [Stem Cells Translational Medicine] |
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| As soon as the first COVID-19 vaccines get approved, a staggering global need will confront limited supplies. Many health experts say it’s clear who should get the first shots: health care workers around the world, then people at a higher risk of severe disease, then those in areas where the disease is spreading rapidly, and finally, the rest of us. [ScienceInsider] |
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| As deaths from COVID-19 approach 150,000 in the United States and cases continue to rise alarmingly in many regions of the country, there are strong signs that the government is suppressing a public-health approach to controlling the pandemic. [Nature News] |
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| September 30 – October 3 Virtual |
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| Huntington Medical Research Institutes – Pasadena, California, United States |
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| The University of Texas Southwestern Medical Center – Dallas, Texas, United States |
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| University of Maryland – Baltimore, Maryland, United States |
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| Northwestern University – Chicago, Illinois, United States |
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| Columbia University – New York, New York, United States |
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