 | | Vol. 12.37 – 24 September, 2020 |
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| Investigators showed that a phosphorylation of threonine-107 in the Glyoxalase 1 protein, mediated by Ca2+/calmodulin-dependent kinase II delta, is associated with elevated catalytic efficiency of Glo1.
[Cell Reports] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| Researchers showed that a single human aorta-gonad-mesonephros region hematopoietic stem cell (HSC) could generate 600–1,600 functional daughter HSCs.
[Stem Cell Reports] |
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| Investigators used tandem mass tag labeling technology followed by tandem mass spectrometry to compare the peptidomic profile of preterm and term umbilical cord MSC conditioned medium.
[Stem Cell Research & Therapy] |
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| Researchers investigated the mechanism by which ibrutinib induces thrombocytopenia using cord blood CD34+ hematopoietic stem cells, a human megakaryoblastic cell line, and C57BL/6 mice.
[Thrombosis and Haemostasis] |
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| The authors investigated the benefit of the association of human umbilical cord MSCs with lodenafil, a phosphodiesterase-5 inhibitor, in an animal model of pulmonary arterial hypertension.
[Cells] |
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| Scientists report cord blood transplantation outcomes of 97 children with Hurler syndrome after a busulfan pharmacokinetic targeted myeloablative conditioning regimens from 2004 to 2016.
[Biology of Blood and Marrow Transplantation] |
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| Adenoviral vectors carrying genes encoding vascular endothelial growth factor, glial cell-derived neurotrophic factor and neural cell adhesion molecule or gene engineered umbilical cord blood mononuclear cells overexpressing recombinant vascular endothelial growth factor, glial cell-derived neurotrophic factor, and neural cell adhesion molecule were intrathecally injected before distal occlusion of the middle cerebral artery in rats.
[International Journal of Molecular Sciences] |
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| The authors provide a comprehensive overview on the progression of clinical trials for retinal degeneration treatment using four types of stem/progenitor cell-based transplantation to replace degenerative retinal cells and/or to supplement trophic factors from the aspects of safety, effectiveness and their respective advantages and disadvantages.
[Cell Death & Disease] |
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| The Medical Research Council (MRC) and the Japan Agency for Medical Research and Development (AMED) have joined forces to support eight new Regenerative Medicine research partnerships. In this landmark collaboration, MRC and AMED will make a total of almost £7 million available to support collaborative projects that seek to advance regenerative approaches towards clinical use.
[Medical Research Council] |
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| April 12- April 15 2021
Breckenridge, Colorado, United States |
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| | Icahn School of Medicine at Mount Sinai – New York, New York, United States |
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| | University of Miami – Miami, Flordia, United States |
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| | Purdue University – West Lafayette, Indiana, United States |
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| | University of Massachusetts – Amherst, Massachusetts, United States |
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| | Huntington Medical Research Institutes – Pasadena, California, United States |
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