| Vol. 12.01 – 14 January, 2021 |
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| Scientists combined bulk and single-cell transcriptional profiling of lymphoid cells, myeloid cells, and hematopoietic stem-progenitor cells from fetal, perinatal, and adult developmental stages to demonstrate that the fetal-to-adult transition occurred progressively along a continuum of maturity. [Cell Reports] |
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PUBLICATIONSRanked by the impact factor of the journal |
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| Researchers investigated freshly isolated, uncultured umbilical cord (UC)-MSCs by single-cell RNA sequencing and found two populations of UC-MSCs. [Stem Cell Research & Therapy] |
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| Human umbilical cord-derived MSCs were successfully cultured and identified, and exosomes were isolated from the supernatant by ultracentrifugation. [Stem Cell Research & Therapy] |
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| Scientists stimulated freshly isolated umbilical blood mononuclear cells with lysates of E. faecalis, S. agalacticae, and S. aureus collected from pregnant women in preterm labor. [International Journal of Molecular Sciences] |
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| Researchers obtained third trimester amniotic fluid from term cesarean delivery and isolated and expanded MSCs in vitro. They then generated ten mm wounds in Leprdb/db diabetic mouse skin, and splinted them open to allow for humanized wound modeling. [Journal of Translational Medicine] |
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| The authors hypothesized that modulation of oxygen conditions during uman amniotic fluid stem cell generation enriches soluble bioactive factors and confers enhanced regenerative and cardioprotective effects on cardiovascular cells. [Scientific Reports] |
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| Malaria infection in the collected maternal peripheral, placental, umbilical cord samples was determined microscopically, and ELISA was used to measure the plasma levels IL-4, IL-6, IL-10, IL-17A, and INF γ in the collected positive and negative malaria samples. [Malaria Journal] |
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| Investigators introduce the development of induced pluripotent stem cells (iPSCs), the currently established iPSC disease models, and artificial organoids related to neurodevelopmental impairments. [International Journal of Medical Sciences] |
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| Bone Therapeutics announced it has treated the first patient for the ALLOB Phase IIb clinical study in patients with difficult-to-heal tibial fractures. The successful completion of Bone Therapeutics’ ALLOB trials would further demonstrate the promise of mesenchymal stromal derived cell therapies for the treatment of other underserved conditions. [Bone Therapeutics SA] |
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| March 14 – 17, 2021 Virtual |
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| University of Colorado – Aurora, Colorado, United States |
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| STEMCELL Technologies, Inc. – Burnaby, British Columbia, Canada |
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| Fondazione Human Technopole – Milan, Italy |
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| Columbia University Medical Center – New York, New York, United States |
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| St. Jude Children’s Research Hospital – Memphis, Tennessee, United States |
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