Cord Blood News Volume 13.14 | Apr 22 2021

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    Justin.choi
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    2021-02-22 | CBN 13.13


    Cord Blood News by STEMCELL Technologies
    Vol.13.14 – 22 April, 2021
    TOP STORY

    Fetal Lung Underdevelopment Is Rescued by Administration of Amniotic Fluid Stem Cell Extracellular Vesicles in Rodents

    The authors describe a stem cell-based approach in rodents that enhanced fetal lung development via the administration of extracellular vesicles derived from amniotic fluid stem cells
    [Science Translational Medicine]

    Abstract
    Image of erythroblasts which were simply & efficiently generated from PSCs using the STEMdiff Erythroid Kit.
    PUBLICATIONSRanked by the impact factor of the journal

    Stem Cells for Bronchopulmonary Dysplasia in Preterm Infants: A Randomized Controlled Phase II Trial

    Scientists investigated the therapeutic efficacy of MSCs for bronchopulmonary dysplasia in premature infants.
    [Stem Cells Translational Medicine]

    Full ArticleEditorial

    Mesenchymal Stromal Cells from Different Parts of Umbilical Cord: Approach to Comparison & Characteristics

    Researchers characterized and compared MSCs from three regions of the umbilical cord: Wharton’s Jelly, the perivascular space and the umbilical membrane.
    [Stem Cell Reviews and Reports]

    Full Article

    Selenomethionine Protects Hematopoietic Stem/Progenitor Cells against Cobalt Nanoparticles by Stimulating Antioxidant Actions and DNA Repair Functions

    The authors investigated the mechanism underlying the toxic effect of cobalt nanoparticles (CoNPs) on HSCs/hematopoietic progenitor cells and to determine the protective effect of selenomethionine against CoNPs in vitro and in vivo.
    [Aging]

    Full Article

    Exosome-Shuttled miR-7162-3p from Human Umbilical Cord Derived Mesenchymal Stem Cells Repair Endometrial Stromal Cell Injury by Restricting APOL6

    A damaged-embryonic stem cell (ESC) model and the umbilical cord (UC) MSC co-culture system were established, while GW4869, a noncompetitive neutral sphingomyelinase inhibitor, was used to investigate the effects of UCMSC-exosomes on mifepristone-induced ESC injury.
    [Archives of Biochemistry and Biophysics]

    Abstract

    Human Umbilical Cord-Derived Mesenchymal Stem Cells and Their Chondroprogenitor Derivatives Reduced Pain and Inflammation Signaling and Promote Regeneration in a Rat Intervertebral Disc Degeneration Model

    Investigators differentiated human umbilical cord (hUC)-MSCs into chondrocyte-like cells and to elucidate their feasibility and efficacy in the degenerated Intervertebral disc rat model.
    [Molecular and Cellular Biochemistry]

    Abstract

    Evaluation of Potential Application of Wharton’s Jelly-Derived Human Mesenchymal Stromal Cells and Its Conditioned Media for Dermal Regeneration Using Rat Wound Healing Model

    Researchers comparatively evaluated the wound healing potential of xeno-free human umbilical cord-derived MSCs and the conditioned media in a full-thickness excision wound model in rats.
    [Cell Tissues Organs]

    Abstract

    The Effect of Erythropoietin and Umbilical Cord-Derived Mesenchymal Stem Cells on Nerve Regeneration in Rats with Sciatic Nerve Injury

    Scientists investigated the effects of umbilical cord-derived mesenchymal stem cells and erythropoietin on nerve regeneration in the sciatic nerve ‘crush injury’ in a rat model.
    [Journal of Chemical Neuroanatomy]

    Abstract

    Microscopy images of pluripotent stem cells (PSCs) and PSC-derived cells for the #StemCellfie contest.
    REVIEWS

    Cardiac Differentiation of Mesenchymal Stem Cells: Impact of Biological and Chemical Inducers

    The authors highlight the impact and recent trends in employing biological and chemical inducers on cardiac differentiation of MSCs.
    [Stem Cell Reviews and Reports]

    Full ArticleGraphical Abstract
    INDUSTRY AND POLICY NEWS

    NIH Reverses Limits on Human Fetal Tissue Research

    A new ruling removes the requirement that grants and proposals using the material receive approval from an ethical review board, reverting to the process in place before 2019.
    [The Scientist]

    Full Article

    City of Hope Enters Licensing Agreements with CytoImmune Therapeutics Inc. to Develop Portfolio of Chimeric Antigen Receptor-Natural Killer Therapies

    City of Hope and CytoImmune Therapeutics Inc. have entered into worldwide exclusive license agreements to several patent applications related to methods to generate large numbers of fully functional natural killer (NK) cells derived from umbilical cord blood and compositions of chimeric receptors (CAR) for targeting NK cells to tumors.
    [CytoImmune Therapeutics, Inc. (BusinessWire, Inc)]

    Press Release
    FEATURED EVENT

    ISCT 2021

    May 26 – 28, 2021
    Virtual

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    JOB OPPORTUNITIES

    Research Assistant – Starstem NanoSTARS

    National University of Ireland Galway – Galway, Ireland

    Postdoctoral Fellow or Research Scientist – Cell and Gene Therapy of Cancer

    Rutgers University – New Brunswick, New Jersey, United States

    Journal Editor – Blood Cancer Discovery and Cancer Immunology

    American Association for Cancer Research – Boston, Massachusetts, United States

    Postdoctoral Fellow – Myeloma Tumor Microenvironment

    Moores Cancer Center – La Jolla, California, United States

    Assistant Professor – Hematology

    University of Washington – Seattle, Washington, United States

    > See All Jobs

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