Cord Blood News Volume 13.16 | May 6 2021

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    CBN 13.16 | May 6 2021


    Cord Blood News by STEMCELL Technologies
    Vol. 13.16 – 6 May, 2021
    TOP STORY

    Allogeneic Hematopoietic Cell Transplantation with Cord Blood versus Mismatched Unrelated Donor with Post-Transplant Cyclophosphamide in Acute Myeloid Leukemia

    Scientists compared the allogeneic hematopoietic cell transplantation (allo-HCT) outcomes of cord blood transplantation versus single-allele-mismatched mismatched unrelated donor allo-HCT with post-transplant cyclophosphamide in acute myeloid leukemia.
    [Journal of Hematology & Oncology]

    Full Article

    View tips on how to organize your lab notebooks, references and protocols.
    PUBLICATIONSRanked by the impact factor of the journal

    Amnion and Umbilical Cord–Derived Products in Sports Medicine: From Basic Science to Clinical Application

    A cord blood product was analyzed by three methods for cell viability, two methods for assessment of cell morphology and cell type, multicolor flow cytometry to identify stem cells, and enzyme-linked immunosorbent assay.
    [The American Journal of Sports Medicine]

    Abstract

    Extracellular Vesicles from Human Umbilical Cord Mesenchymal Stem Cells Facilitate Diabetic Wound Healing through MiR-17-5p-mediated Enhancement of Angiogenesis

    Researchers investigated the effects of extracellular vehicles secreted by human umbilical cord mesenchymal stem cells on angiogenesis under high glucose conditions in vivo and in vitro and to explore the underlying mechanisms.
    [Stem Cell Reviews and Reports]

    AbstractGraphical Abstract

    Consecutive Daily Administration of Intratracheal Surfactant and Human Umbilical Cord-Derived Mesenchymal Stem Cells Attenuates Hyperoxia-Induced Lung Injury in Neonatal Rats

    The authors evaluated the effects of two consecutive days of intratracheal administration of surfactant and human umbilical cord-MSC on hyperoxia-induced lung injury.
    [Stem Cell Research & Therapy]

    Full Article

    Umbilical Cord-Derived MSC and Hyperbaric Oxygen Therapy Effectively Protected the Brain in Rat after Acute Intracerebral Hemorrhage

    Scientists tested the hypothesis that combined therapy with human umbilical cord‐derived MSCs and hyperbaric oxygen was superior to either one on preserving neurological function and reducing brain hemorrhagic volume in rat after acute intracerebral hemorrhage induced by intracranial injection of collagenase.
    [Journal of Cellular and Molecular Medicine]

    Full Article

    Getting enough cord blood HSCs for transplantation isn't easy. But she's paving the way. Watch Suzan Imren's webinar.
    REVIEWS

    Mesenchymal Stromal Cell Therapy for COVID-19: Which? When? And How Much?

    The authors compile and discuss study design data from ongoing clinical trials to address the key questions of ‘which’ tissue source, donor profile, isolation technique, culture conditions, long-term culture and cryopreservation for MSCs.
    [Cytotherapy]

    Full ArticleGraphical Abstract

    Role of Ex Vivo Expanded Mesenchymal Stromal Cells in Determining Hematopoietic Stem Cell Transplantation Outcome

    Investigators explore the several mechanisms through which MSCs impact on the supportive activity of the bone marrow niche and regulate hematopoietic stem and progenitor cell homeostasis.
    [Frontiers in Cell and Developmental Biology]

    Full Article

    INDUSTRY AND POLICY NEWS

    FDA Approves Orgenesis IDE for Pilot Clinical Trial of its Tissue Genesis Icellator2® to Treat ARDS Resulting from COVID-19 Infection

    Orgenesis, Inc. announced it has been granted Investigational Device Exemption (IDE) approval by the FDA to conduct a first-in-human feasibility study of the Tissue Genesis Icellator2® to treat Acute Respiratory Distress Syndrome (ARDS) resulting from COVID-19 infection.
    [Orgenesis, Inc. (GlobeNewswire, Inc.)]

    Press Release

    FEATURED EVENT

    Congress of the European Hematology Association

    June 9 – 17, 2021
    Virtual

    > See All Events

    JOB OPPORTUNITIES

    Senior Scientist – Stem Cell Biology

    Ncardia- Leiden, The Netherlands

    Chair – Gastrointestinal and Pancreatic Cancer Research

    Indiana University School of Medicine – Indianapolis, Indiana, United States

    Postdoctoral Researcher Fellowships – Center for Stem Cell and Regenerative Medicine

    Zhejiang University – Zhejiang, China

    Senior Research Assistant – Leukemia

    University of Texas MD Anderson Cancer Center – Houston, Texas, United States

    Postdoctoral Fellow – Myeloma Tumor Microenvironment

    Moores Cancer Center – La Jolla, California, United States

    > See All Jobs

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