| Vol. 13.20 – 3 June, 2021 |
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| Scientists induced asphyxia in fetal sheep via umbilical cord occlusion until mean arterial blood pressure fell from 55 ± 3 mmHg in sham controls to 18-20 mmHg. [Journal of Pineal Research] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| PMNT was confirmed to promote human umbilical cord-derived MSC proliferation in a serum-free medium by driving cell cycles and up-regulating gene expression in the pathways of biosynthesis and the metabolism. [ACS Applied Materials & Interfaces] |
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| Scientists explored the feasibility of generating bivalent-Leuk-STs directed against Wilms tumor 1 and preferentially expressed antigen in melanoma from umbilical cord blood units disqualified for allogeneic hematopoietic stem cell transplantation. [British Journal of Haematology] |
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| Researchers cultured human amniotic epithelial cells (hAECs) and extracted exosomes from culture supernatants. They established a stable acute myocardial infarction model in rats and treated them with hAECs, exosomes, or PBS. [Aging] |
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| Scientists investigated the effect of extracellular vesicles derived from human umbilical cord-MSC on the clinical score and inflammatory/anti-inflammatory cytokines on the experimental autoimmune encephalomyelitis mouse model. [Scientific Reports] |
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| Investigators aimed to fabricate a Matrigel scaffold loaded with human umbilical cord-derived MSCs and explore its potential to restore ovarian function and repair ovarian structures in vitro and in vivo. [Stem Cells and Development] |
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| Researchers investigated the safety and potential therapeutic efficacy of allogeneic administration of umbilical cord-derived MSCs as a supplementary intervention in combination with standard COPD medication treatments in patients with moderate-to-severe COPD. [BMJ Open] |
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| The authors compared the ability of regulatory T cells (Treg) + mesenchymal stromal cells (MSC) combination therapy, as well as MSC and Treg monotherapies, to improve blood brain barrier permeability in vivo and suppress inflammation in vitro. [PLOS One] |
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| Investigators provide a detailed description of the functional properties of MSCs and extracellular vesicles and their potential clinical applications, with a special focus on pain treatment. [British Journal of Pharmacology] |
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| A systematic approach to molecular monitoring, histopathological assessment and chimerism testing is proposed. These proposed recommendations aim to increase the accuracy and uniformity of reporting and to thereby facilitate the development of more consistent approaches. [Leukemia] |
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| The International Society for Stem Cell Research relaxed the famous 14-day rule on culturing human embryos in its latest research guidelines. [Nature News] |
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| August 18 – 19, 2021 Virtual |
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| UT Southwestern Medical Center – Dallas, Texas, United Statess |
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| Memorial Sloan Kettering Cancer Center – New York, New York, United States |
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| University of British Columbia – Vancouver, British Columbia, Canada |
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| Columbia University Medical Center – New York, New York, United States |
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| Zhejiang University – Zhejiang, China |
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