Cord Blood News Volume 13.21 | Jun 10 2021

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    Justin.choi
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    2021-06-10 | CBN 13.21


    Cord Blood News by STEMCELL Technologies
    Vol. 13.21 – 10 June, 2021
    TOP STORY

    Continuous Activation of Polymorphonuclear Myeloid-Derived Suppressor Cells during Pregnancy Is Critical for Fetal Development

    Scientists reported that the activation of polymorphonuclear myeloid-derived suppressor cells during pregnancy was closely associated with fetal growth.
    [Cellular & Molecular Immunology]

    Abstract

    Request your free copy of the 'Directed Differentiation of Pluripotent Stem Cells' Wallchart
    PUBLICATIONSRanked by the impact factor of the journal

    PRL-1 Overexpressed Placenta-Derived Mesenchymal Stem Cells Suppress Adipogenesis in Graves’ Ophthalmopathy through SREBP2/HMGCR Pathway

    Investigators constructed PRL-1 overexpressed human placental MSCs in an attempt to enhance the suppressive function of adipogenesis in Graves’ ophthalmopathy animal models.
    [Stem Cell Research & Therapy]

    Full Article

    A Novel Therapeutic Approach for Inflammatory Bowel Disease by Exosomes Derived from Human Umbilical Cord Mesenchymal Stem Cells to Repair Intestinal Barrier via TSG-6

    Two separate dextran sulfate sodium and 2,4,6-trinitrobenzenesulfonic acid induced inflammatory bowel disease mouse models were intraperitoneally administered MSCs-Exo extracted from human umbilical cord MSC culture supernatant.
    [Stem Cell Research & Therapy]

    Full Article

    Differential Localization of Serotoninergic System Elements in Human Amniotic Epithelial Cells

    Researchers investigated the expression and distribution of the main components of the serotoninergic system in human amniotic tissue and in human amniotic epithelial cells in vitro, as an alternative model of early human embryo development.
    [Biology of Reproduction]

    Abstract

    VEGF165 Gene-Modified Human Umbilical Cord Blood Mesenchymal Stem Cells Protect against Acute Liver Failure in Rats

    Human umbilical cord blood-MSCs were infected with the adenovirus expressing GFP-VEFG fusion protein to overexpress VEGF165 or the adenovirus expressing GFP as control.
    [Journal of Gene Medicine]

    Abstract

    Human Umbilical Cord Mesenchymal Stromal Cell Treatment of Severe COVID-19 Patients: A Three-Month Follow-Up Study Following Hospital Discharge

    In this three-month follow-up study, investigators examined discharged patients who had received human umbilical cord-MSC therapy to assess the safety of this therapy and the health-related quality of life of these patients.
    [Stem Cells and Development]

    Abstract

    Return to your lab safely and efficiently with these guides and resources so that you can focus more on moving your research goals forward.
    REVIEWS

    Human Umbilical Cord Mesenchymal Stem Cells in Type 2 Diabetes Mellitus: The Emerging Therapeutic Approach

    The authors focus on the latest research and applications of human-derived umbilical cord MSC in the treatment and management of T2DM, exploring and systematizing the key effects of both umbilical cord MSC and its factor-rich secretome accordingly with the major complications associated to T2DM.
    [Cell and Tissue Research]

    Abstract

    INDUSTRY AND POLICY NEWS

    Calidi Biotherapeutics Announces Partnership with GenScript ProBio for Distribution of its SuperNova-1 Technology

    Calidi Biotherapeutics, Inc. announced its partnership with GenScript ProBio for assistance in the advertisement and distribution of Calidi’s proprietary technology platform: SuperNova-1 (SNV-1). The SNV-1 platform is composed of allogeneic, adipose-derived-MSC loaded with an oncolytic agent such as the vaccinia virus.
    [Calidi Biotherapeutics, Inc.]

    Press Release

    FEATURED EVENT

    EMBO: Molecular Mechanisms of Aging and Regeneration: From Hydra to Humans

    September 6 – 10, 2021
    Virtual

    > See All Events

    JOB OPPORTUNITIES

    Postdoctoral Position – Cell and Developmental Biology

    University of Pisa – Pisa, Italy

    Postdoctoral Positions – Hematopoiesis and Leukemia

    UT Southwestern Medical Center – Dallas, Texas, United Statess

    Laboratory Technologist – Histocompatibility

    Memorial Sloan Kettering Cancer Center – New York, New York, United States

    Postdoctoral Fellow – Stem Cell Derived Therapeutics

    University of British Columbia – Vancouver, British Columbia, Canada

    Postdoctoral Position – Stemness Control in Pluripotent and Cancer Cells

    Columbia University Medical Center – New York, New York, United States

    > See All Jobs

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