Cord Blood News Volume 13.22 | Jun 17 2021

May 12, 2022

118

2021-06-17 | CBN 13.22

Cord Blood News by STEMCELL Technologies

Vol. 13.22 – 17 June, 2021

TOP STORY

Human Umbilical Cord Mesenchymal Stem Cell Transfusion in Immune Non-Responders with AIDS: A Multicenter Randomized Controlled Trial

Scientists examined the safety and efficacy of human umbilical cord mesenchymal stem cell infusion for immune non-responder patients with chronic HIV-1 infection, who represented an unmet medical need even in the era of efficient antiretroviral therapy.
[Signal Transduction and Targeted Therapy]

Full Article

Scientific resources to support your hematopoiesis research. Learn More!

PUBLICATIONSRanked by the impact factor of the journal

Human Cord Blood B Cells Differ from the Adult Counterpart by Conserved Ig Repertoires and Accelerated Response Dynamics

The authors provided a comprehensive molecular and functional comparison of B cell subsets from umbilical cord blood and adult peripheral blood.
[Journal of Immunology]

Abstract

Cord Blood DNA Methylation Modifications in Infants Are Associated with White Matter Microstructure in the Context of Prenatal Maternal Depression and Anxiety

To determine if infants of women with depression and anxiety symptoms exhibited epigenetic modifications linked to neurodevelopmental changes, 52 umbilical cord bloods were profiled.
[Scientific Reports]

Full Article

iNKT Cells Coordinate Immune Pathways to Enable Engraftment in Nonconditioned Hosts

Using a human umbilical cord blood xenotransplantation model, researchers showed that co-transplanted allogeneic CD4⁺ iNKT cells interacted with monocytes and T cells in the graft to coordinate pro-hematopoietic and immunoregulatory pathways.
[Life Science Alliance]

Full Article

Incidence and Risk Factors of Late-Onset Hemorrhagic Cystitis after Single Umbilical Cord Blood Transplantation with Myeloablative Conditioning Regimen

Scientists explored the incidence and risk factors of late-onset hemorrhagic cystitis in patients undergoing single umbilical cord blood transplantation for hematological malignancies.
[International Journal of Hematology]

Abstract

Prognostic Impacts of Peripheral Blood Erythroblasts after Single-Unit Cord Blood Transplantation

Researchers investigated the impact of erythroblasts on transplant outcomes on 225 adult patients who underwent single-unit cord blood transplantation at our single institute.
[International Journal of Laboratory Hematology]

Abstract

The StemSpan™ T Cell Generation Kit is designed to promote differentiation of HSPCs into T cells in stroma- and serum-free culture conditions.

REVIEWS

Human Umbilical Cord Tissue-Derived Mesenchymal Stromal Cells as Adjuvant Therapy for Myocardial Infarction: A Review of Current Evidence Focusing on Pre-clinical Large Animal Models and Early Human Trials

The available evidence concerning umbilical cord-derived MSCs in acute myocardial infarction is reviewed, focusing on large animal pre-clinical studies and early human trials.
[Cytotherapy]

Abstract

Emerging Understanding of Apoptosis in Mediating Mesenchymal Stem Cell Therapy

Investigators summarize the emerging understanding of apoptosis in mediating mesenchymal stem cell transplant, highlighting the potential of apoptotic extracellular vesicles as cell-free therapeutics.
[Cell Death & Disease]

Full Article

Mesenchymal Stromal Cell-Derived Exosomes in Cardiac Regeneration and Repair

Scientists summarize the potential mechanisms and therapeutic effects of MSC-derived exosomes in cardiac regeneration and repair and provide evidence to support their clinical application.
[Stem Cell Reports]

Full Article Graphical Abstract

INDUSTRY AND POLICY NEWS

Calidi Biotherapeutics Announces Partnership with GenScript ProBio for Distribution of its SuperNova-1 Technology

Calidi Biotherapeutics, Inc. announced its partnership with GenScript ProBio for assistance in the advertisement and distribution of Calidi’s proprietary technology platform: SuperNova-1 (SNV-1). The SNV-1 platform is composed of allogeneic, adipose-derived-MSC loaded with an oncolytic agent such as the vaccinia virus.
[Calidi Biotherapeutics, Inc. (Business Wire, Inc.)]

Press Release

FEATURED EVENT

Human Umbilical Cord Mesenchymal Stem Cell Transfusion in Immune Non-Responders with AIDS: A Multicenter Randomized Controlled Trial

Human Cord Blood B Cells Differ from the Adult Counterpart by Conserved Ig Repertoires and Accelerated Response Dynamics

Cord Blood DNA Methylation Modifications in Infants Are Associated with White Matter Microstructure in the Context of Prenatal Maternal Depression and Anxiety

iNKT Cells Coordinate Immune Pathways to Enable Engraftment in Nonconditioned Hosts

Incidence and Risk Factors of Late-Onset Hemorrhagic Cystitis after Single Umbilical Cord Blood Transplantation with Myeloablative Conditioning Regimen

Prognostic Impacts of Peripheral Blood Erythroblasts after Single-Unit Cord Blood Transplantation

Human Umbilical Cord Tissue-Derived Mesenchymal Stromal Cells as Adjuvant Therapy for Myocardial Infarction: A Review of Current Evidence Focusing on Pre-clinical Large Animal Models and Early Human Trials

Emerging Understanding of Apoptosis in Mediating Mesenchymal Stem Cell Therapy

Mesenchymal Stromal Cell-Derived Exosomes in Cardiac Regeneration and Repair

Calidi Biotherapeutics Announces Partnership with GenScript ProBio for Distribution of its SuperNova-1 Technology

Emerging Therapies at the Intersection of Genetic and Cellular Technologies

> See All Events

Postdoctoral Research Associate – Tissue Development and Regeneration

Postdoctoral Positions – Hematopoiesis and Leukemia

Laboratory Technologist – Histocompatibility

Postdoctoral Position – Cell and Developmental Biology

Postdoctoral Position – Stemness Control in Pluripotent and Cancer Cells

> See All Jobs